Genome editing technologies: defining a path to clinic

Jacqueline Corrigan-Curay; Marina O'Reilly; Donald B Kohn; Paula M Cannon; Gang Bao; Frederic D Bushman; Dana Carroll; Toni Cathomen; J Keith Joung; David Roth; Michel Sadelain; Andrew M Scharenberg; Christof von Kalle; Feng Zhang; Robert Jambou; Eugene Rosenthal; Morad Hassani; Aparna Singh; Matthew H Porteus

doi:10.1038/mt.2015.54

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Genome editing technologies: defining a path to clinic

Journal article

Open access

Peer reviewed

Genome editing technologies: defining a path to clinic

Jacqueline Corrigan-Curay, Marina O'Reilly, Donald B Kohn, Paula M Cannon, Gang Bao, Frederic D Bushman, Dana Carroll, Toni Cathomen, J Keith Joung, David Roth, …

Molecular therapy, Vol.23(5), pp.796-806

2015-05

DOI: https://doi.org/10.1038/mt.2015.54

PMID: 25943494

Abstract

Genetic Engineering - methods

Animals

DNA Repair

Gene Rearrangement

Humans

Mutagenicity Tests

Translational Medical Research

Models, Animal

Genome

Genomics - methods

DNA Breaks, Double-Stranded

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.54 Molecular & Cell Biology - Genetics; 1.54.1401 Genome Editing
Web Of Science research areas: Biotechnology & Applied Microbiology; Genetics & Heredity; Medicine, Research & Experimental
ESI research areas: Clinical Medicine

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Details

Title: Genome editing technologies: defining a path to clinic
Creators: Jacqueline Corrigan-Curay - National Institutes of Health, Bethesda, Maryland, USA. Electronic address: corrigaja@nhlbi.nih.gov
Marina O'Reilly - National Institutes of Health, Bethesda, Maryland, USA
Donald B Kohn - University of California, Los Angeles, Los Angeles, California, USA
Paula M Cannon - Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Gang Bao - Georgia Institute of Technology, Atlanta, Georgia, USA
Frederic D Bushman - University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania, USA
Dana Carroll - University of Utah, School of Medicine, Salt Lake City, Utah, USA
Toni Cathomen - University Medical Center Freiberg, Freiberg, Germany
J Keith Joung - Massachusetts General Hospital, Charlestown, Massachusetts; Harvard Medical School, Boston, Massachusetts, USA
David Roth - University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania, USA
Michel Sadelain - Memorial Sloan-Kettering Cancer Center, New York, New York, USA
Andrew M Scharenberg - Seattle Children's Research Institute and University of Washington, School of Medicine, Seattle, Washington, USA
Christof von Kalle - National Center for Tumor Diseases and German Cancer Research Center, Heidelberg, Germany
Feng Zhang - Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, USA
Robert Jambou - National Institutes of Health, Bethesda, Maryland, USA
Eugene Rosenthal - National Institutes of Health, Bethesda, Maryland, USA
Morad Hassani - National Institutes of Health, Bethesda, Maryland, USA
Aparna Singh - National Institutes of Health, Bethesda, Maryland, USA
Matthew H Porteus - Stanford University, California, Stanford, California, USA
Publication Details: Molecular therapy, Vol.23(5), pp.796-806
Grant note: R01 GM078571 / NIGMS NIH HHS R01 AI082020 / NIAID NIH HHS
Academic Unit: Miller School of Medicine; UMMG Dept of Medicine - Nephrology & Hypertension Div
Language: English
Resource Type: Journal article
PMID: 25943494
Record Identifier: 991031600478502976