Genome-wide mRNA and miRNA expression data analysis to screen for markers involved in sarcomagenesis in human chondrosarcoma cell lines

Biju Issac; Karina Galoian; Toumy Guettouche; Loida Navarro; H. Thomas Temple

doi:10.1016/j.gdata.2014.10.001

Back

Genome-wide mRNA and miRNA expression data analysis to screen for markers involved in sarcomagenesis in human chondrosarcoma cell lines

Journal article

Open access

Peer reviewed

Genome-wide mRNA and miRNA expression data analysis to screen for markers involved in sarcomagenesis in human chondrosarcoma cell lines

Biju Issac, Karina Galoian, Toumy Guettouche, Loida Navarro and H. Thomas Temple

Genomics data, Vol.2(C), pp.320-324

2014-12

DOI: https://doi.org/10.1016/j.gdata.2014.10.001

PMCID: PMC4536178

PMID: 26484120

Abstract

miRNAs

Microarray

Bioinformatics

Human chrondrosarcoma

mRNA expression

Genes and miRNAs involved in sarcomagenesis related pathways are unknown and therefore signaling events leading to mesenchymal cell transformation to sarcoma are poorly elucidated. Exiqon and Illumina microarray study on human chondrosarcoma JJ012 and chondrocytes C28 cell lines to compare and analyze the differentially expressed miRNAs and their gene targets was recently published in the Journal Tumor Biology in 2014. Here we describe in details the contents and quality controls for the miRNA and gene expression data associated with the study that is relevant to this dataset.

Files and links (1)

url

https://doi.org/10.1016/j.gdata.2014.10.001View

Published (Version of record) Open

Metrics

12 Record Views

1 Times Cited - Web of Science

See more details

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

Source: InCites

Details

Title: Genome-wide mRNA and miRNA expression data analysis to screen for markers involved in sarcomagenesis in human chondrosarcoma cell lines
Creators: Biju Issac - Biostatistics and Bioinformatics Core/Division of Bioinformatics, Sylvester comprehensive Cancer Center, University of Miami, 1550 NW 10th Ave, Fox 304A, Miami, FL 33136, USA
Karina Galoian - Department of Orthopaedic Surgery, Miller School of Medicine, University of Miami, 1600 NW 10th Ave, S 8012, Miami, FL 33136, USA
Toumy Guettouche - Children's Hospital of Philadelphia, Center of Applied Genomics, 3615 Civic center Blvd, Philadelphia, PA 19104-4318, USA
Loida Navarro - Oncogenomics Core, Sylvester Comprehensive Cancer Center, University of Miami, 1501 NW 10th Ave, BRB 542 B.02, Miami FL 33136, USA
H. Thomas Temple - Department of Orthopaedic Surgery and University of Miami Tissue Bank Division, Miller School of Medicine, University of Miami, 1400 NW 12th Ave, UMH, East Bldg 4036, Miami, FL 33136, USA
Publication Details: Genomics data, Vol.2(C), pp.320-324
Publisher: Elsevier Inc
Academic Unit: Miller School of Medicine; UMMG Department of Orthopaedics; UMMG Dept of Orthopaedics - UHealth Sports Medicine
Language: English
Resource Type: Journal article
PMID: 26484120
PMCID: PMC4536178
Record Identifier: 991031577797802976