References: Arita, Y., Kihara, S., Ouchi, N., Takahashi, M., Maeda, K., Miyagawa, J., Matsuzawa, Y., Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity (1999) Biochemical and Biophysical Research Communications, 257, pp. 79-83. , https://doi.org/10.1006/bbrc.1999.0255;
Ban, B., Bai, B., Zhang, M., Hu, J., Ramanjaneya, M., Tan, B.K., Chen, J., Low serum cartonectin/CTRP3 concentrations in newly diagnosed type 2 diabetes mellitus: In vivo regulation of cartonectin by glucose (2014) PLoS ONE, 9;
Choi, K.M., Hwang, S.Y., Hong, H.C., Choi, H.Y., Yoo, H.J., Youn, B.S., Seo, H.S., Implications of C1q/TNF-related protein-3 (CTRP-3) and progranulin in patients with acute coronary syndrome and stable angina pectoris (2014) Cardiovascular Diabetology, 13, p. 14. , https://doi.org/10.1186/1475-2840-13-14;
Choi, K.M., Hwang, S.Y., Hong, H.C., Yang, S.J., Choi, H.Y., Yoo, H.J., Baik, S.H., C1q/TNF-related protein-3 (CTRP-3) and pigment epithelium-derived factor (PEDF) concentrations in patients with type 2 diabetes and metabolic syndrome (2012) Diabetes, 61, pp. 2932-2936. , https://doi.org/10.2337/db12-0217;
Deng, W., Li, C., Zhang, Y., Zhao, J., Yang, M., Tian, M., Yang, G., Serum C1q/TNF-related protein-3 (CTRP3) levels are decreased in obesity and hypertension and are negatively correlated with parameters of insulin resistance (2015) Diabetology & Metabolic Syndrome, 7, p. 33. , https://doi.org/10.1186/s13098-015-0029-0;
Geerling, J.J., Boon, M.R., van der Zon, G.C., van den Berg, S.A., van den Hoek, A.M., Lombes, M., Guigas, B., Metformin lowers plasma triglycerides by promoting VLDL-triglyceride clearance by brown adipose tissue in mice (2014) Diabetes, 63, pp. 880-891. , https://doi.org/10.2337/db13-0194;
Hirose, H., Yamamoto, Y., Seino-Yoshihara, Y., Kawabe, H., Saito, I., Serum high-molecular-weight adiponectin as a marker for the evaluation and care of subjects with metabolic syndrome and related disorders (2010) Journal of Atherosclerosis and Thrombosis, 17, pp. 1201-1211. , https://doi.org/10.5551/jat.6106;
Hofmann, C., Chen, N., Obermeier, F., Paul, G., Buchler, C., Kopp, A., Schaffler, A., C1q/TNF-related protein-3 (CTRP-3) is secreted by visceral adipose tissue and exerts antiinflammatory and antifibrotic effects in primary human colonic fibroblasts (2011) Inflammatory Bowel Diseases, 17, pp. 2462-2471. , https://doi.org/10.1002/ibd.21647;
Kishore, U., Gaboriaud, C., Waters, P., Shrive, A.K., Greenhough, T.J., Reid, K.B., Arlaud, G.J., C1q and tumor necrosis factor superfamily: Modularity and versatility (2004) Trends in Immunology, 25, pp. 551-561;
Kopp, A., Bala, M., Buechler, C., Falk, W., Gross, P., Neumeier, M., Schaffler, A., C1q/TNF-related protein-3 represents a novel and endogenous lipopolysaccharide antagonist of the adipose tissue (2010) Endocrinology, 151, pp. 5267-5278. , https://doi.org/10.1210/en.2010-0571;
Kopp, A., Bala, M., Weigert, J., Buchler, C., Neumeier, M., Aslanidis, C., Schaffler, A., Effects of the new adiponectin paralogous protein CTRP-3 and of LPS on cytokine release from monocytes of patients with type 2 diabetes mellitus (2010) Cytokine, 49, pp. 51-57. , https://doi.org/10.1016/j.cyto.2009.10.001;
Li, Y., Wright, G.L., Peterson, J.M., C1q/TNF-related protein 3 (CTRP3) function and regulation (2017) Comprehensive Physiology, 7, pp. 863-878;
Maeda, T., Abe, M., Kurisu, K., Jikko, A., Furukawa, S., Molecular cloning and characterization of a novel gene, CORS26, encoding a putative secretory protein and its possible involvement in skeletal development (2001) Journal of Biological Chemistry, 276, pp. 3628-3634;
Maeda, T., Jikko, A., Abe, M., Yokohama-Tamaki, T., Akiyama, H., Furukawa, S., Wakisaka, S., Cartducin, a paralog of Acrp30/adiponectin, is induced during chondrogenic differentiation and promotes proliferation of chondrogenic precursors and chondrocytes (2006) Journal of Cellular Physiology, 206, pp. 537-544. , https://doi.org/10.1002/jcp.20493;
Pajvani, U.B., Du, X., Combs, T.P., Berg, A.H., Rajala, M.W., Schulthess, T., Scherer, P.E., Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivity (2003) Journal of Biological Chemistry, 278, pp. 9073-9085. , https://doi.org/10.1074/jbc.M207198200;
Petersen, P.S., Wolf, R.M., Lei, X., Peterson, J.M., Wong, G.W., Immunomodulatory roles of CTRP3 in endotoxemia and metabolic stress (2016) Physiological Reports, 4 (5);
Peterson, J.M., Identification of cell surface receptors for the novel adipokine CTRP3 (2016) The FASEB Journal, 30, p. 1249.1242;
Peterson, J.M., Seldin, M.M., Wei, Z., Aja, S., Wong, G.W., CTRP3 attenuates diet-induced hepatic steatosis by regulating triglyceride metabolism (2013) American Journal of Physiology. Gastrointestinal and Liver Physiology, 305, pp. G214-G224. , https://doi.org/10.1152/ajpgi.00102.2013;
Peterson, J.M., Wei, Z., Wong, G.W., C1q/TNF-related protein-3 (CTRP3), a novel adipokine that regulates hepatic glucose output (2010) Journal of Biological Chemistry, 285, pp. 39691-39701. , https://doi.org/10.1074/jbc.M110.180695;
Qu, H., Deng, M., Wang, H., Wei, H., Liu, F., Wu, J., Deng, H., Plasma CTRP-3 concentrations in Chinese patients with obesity and type II diabetes negatively correlate with insulin resistance (2015) Journal of Clinical Lipidology, 9, pp. 289-294. , https://doi.org/10.1016/j.jacl.2015.03.006;
Schaffler, A., Weigert, J., Neumeier, M., Scholmerich, J., Buechler, C., Regulation and function of collagenous repeat containing sequence of 26-kDa protein gene product "cartonectin" (2007) Obesity (Silver Spring), 15, pp. 303-313. , https://doi.org/10.1038/oby.2007.566;
Schmid, A., Kopp, A., Hanses, F., Karrasch, T., Schaffler, A., C1q/TNF-related protein-3 (CTRP-3) attenuates lipopolysaccharide (LPS)-induced systemic inflammation and adipose tissue Erk-1/-2 phosphorylation in mice in vivo (2014) Biochemical and Biophysical Research Communications, 452, pp. 8-13. , https://doi.org/10.1016/j.bbrc.2014.06.054;
Shapiro, L., Scherer, P.E., The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor (1998) Current Biology, 8, pp. 335-338. , https://doi.org/10.1016/S0960-9822(98)70133-2;
Tan, B.K., Chen, J., Hu, J., Amar, O., Mattu, H.S., Adya, R., Randeva, H.S., Metformin increases the novel adipokine cartonectin/CTRP3 in women with polycystic ovary syndrome (2013) Journal of Clinical Endocrinology and Metabolism, 98, pp. E1891-E1900. , https://doi.org/10.1210/jc.2013-2227;
Trogen, G., Bacon, J., Li, Y., Wright, G.L., Degroat, A., Hagood, K.L., Peterson, J.M., Transgenic overexpression of CTRP3 prevents alcohol-induced hepatic triglyceride accumulation (2018) American Journal of Physiology-Endocrinology and Metabolism, 315 (5), pp. E949-E960. , https://doi.org/10.1152/ajpendo.00050.2018;
Wagner, R.M., Sivagnanam, K., Clark, W.A., Peterson, J.M., Divergent relationship of circulating CTRP3 levels between obesity and gender: A cross-sectional study (2016) PeerJ, 4;
Waki, H., Yamauchi, T., Kamon, J., Ito, Y., Uchida, S., Kita, S., Kadowaki, T., Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin (2003) Journal of Biological Chemistry, 278, pp. 40352-40363. , https://doi.org/10.1074/jbc.M300365200;
Wolf, R.M., Steele, K.E., Peterson, L.A., Magnuson, T.H., Schweitzer, M.A., Wong, G.W., Lower circulating C1q/TNF-related protein-3 (CTRP3) levels are associated with obesity: A cross-sectional study (2015) PLoS One, 10;
Wong, G.W., Krawczyk, S.A., Kitidis-Mitrokostas, C., Revett, T., Gimeno, R., Lodish, H.F., Molecular, biochemical and functional characterizations of C1q/TNF family members: Adipose-tissue-selective expression patterns, regulation by PPAR-gamma agonist, cysteine-mediated oligomerizations, combinatorial associations and metabolic functions (2008) The Biochemical Journal, 416, pp. 161-177;
Yang, B., Wang, S., Yu, S., Chen, Y., Li, L., Zhang, H., Zhao, Y., C1q/tumor necrosis factor-related protein 3 inhibits oxidative stress during intracerebral hemorrhage via PKA signaling (2016) Brain Research, 1657, pp. 176-184. , https://doi.org/10.1016/j.brainres.2016.11.016;
Yoo, H.J., Hwang, S.Y., Hong, H.C., Choi, H.Y., Yang, S.J., Choi, D.S., Choi, K.M., Implication of progranulin and C1q/TNF-related protein-3 (CTRP3) on inflammation and atherosclerosis in subjects with or without metabolic syndrome (2013) PLoS One, 8. , https://doi.org/10.1371/journal.pone.0055744