Identifying consensus and areas for future research in chondrosarcoma : a report from the Birmingham Orthopaedic Oncology Meeting

Lee M. Jeys; Guy V. Morris; Vineet J. Kurisunkal; Eduardo Botello; Richard A. Boyle; Walid Ebeid; Matthew T. Houdek; Ajay Puri; Pietro Ruggieri; Bernadette Brennan; BOOM Consensus Meeting Participants; Minna K. Laitinen; Santiago Abad Repiso; Hesham Abdelbary; Alejandro Abiad Mejia; Ahmed A. Abood; Juan C. Abril Martin; Adesegun Abudu; Ayman Abu Elhamd; Marthelena Acosta; Keisuke Ae; Manish Agarwal; Vivek Ajit Singh; Toru Akiyama; Ibrahim Alshaygy; Jose I. Albergo; John Alexander; Patricio A. Alfaro; Bugra Alpan; Jose Amaya-Valero; Megan Anderson; Dimosthenis Andreou; Lucas Annabell; Christopher Anthony; Ahmed Aoude; Iraia Arteagoitia-Colino; Apichat Asavamongkolkul; William Aston; Libe Asua Mentxaka; Christine Azzopardi; Thomas Baad-Hansen; Ismail T. Badr; Francisco Baixauli-Garcia; Gavin Baker; Tessa Balach; Giacomo G. Baldi; Janie Barry; Georges Basile; Stefano Bastoni; Mohammad Basuki; Henrik Bauer; Lee Bayliss; Ricardo G. Becker; Angad Bedi; Joseph Benevenia; Francisco Bengoa; Peter Bergh; Marko Bergovec; Nicholas Bernthal; Odion Binitie; David Boddie; Michele Boffano; Patricia Bonilla Huertas; Anna B. Borgognoni; Rajesh Botchu; Jos Bramer; Rahat Brar; Harriet Branford-White; Demien Broekhuis; Samuel E. Broida; Tymoteusz Budny; Zachary D. Burke; Jorge Cabrolier; Jose A. Calvo-Haro; Jorge R. Calvo Tapies; Rodrigo Cardoso; Richard Carey Smith; Pedro I. Carvallo; Nicolas Casales Fresenga; Jose M. Casanova; Oscar Ceballos; Juan L. Cebrian Parra; Sara Chacon Cartaya; Chung M. Chan; Yoon Joo Cho; Peter Choong; Yang-Guk Chung; Dawid Ciechanowicz; Miguel A. Clara-Altamirano; David Clever; Sebastian M. Colina; Luis Consuegra; Cory Couch; Gillian Cribb; Carlos Cuervo; Laurence A. Cusick; Solomon Dadia; Tanios Dagher; Dietmar Dammerer; Mark Davies; Nerys Davies; Luis P. de la Rosa Martino; Francisco J de Santos de la Fuente; Marieke de Vaal; Claudia Deckers; Javier Delgado Obando; Shaneel Deo; Niklas Deventer; Claudia Di Bella; Gregory Domson; Davide M. Donati; Desiree M. Dorleijn; Jacques Du Toit; Debra Dunne; Rodolfo Duran Ciarrochi; Elina Ekman; Ahmed M. El Ghoneimy; Makoto Endo; Levent Eralp; Mahmoud Etaiwi; Scott Evans; Robin Evrard; Will Eward; Alberto Farese; Peter C. Ferguson; Pedro F. Ferreira Cardoso; Fabrice Fiorenza; Michael Flint; Hector Flores; Joao Freitas; Bruno Fuchs; Tomohiro Fujiwara; Philipp T. Funovics; Marcos Galli Serra; Zakareya Gamie; Carlos Garces-Zarzalejo; Aaron Gazendam; Carsten Gebert; Jasper G. Gerbers; Craig Gerrand; Ghaith Abou-Nouar; Michelle Ghert; Kanishka M. Ghosh; Max Gibbons; Luis C. Gomez-Mier; Jesus Gomez-Vallejo; Anne Gomez-Mascard; Marcos R. Gonzalez; Fausto Gonzalez-Lizan; Georg Gosheger; Stuart Goudie; Krista Goulding; Stavros D. Goumenos; Anthony Griffin; Ashish Gulia; Sanjay Gupta; Amit Gupta; Maurice Guzman; Mohammed Haitham; Jendrik Hardes; Francisco Hardoy; Yusuf Hasan; Georg Hauer; Helard Havard; Rex Haydon; John Healey; Nerea Hernandez Gonzalez; Adriana Hernandez-Lopez; Asle Hesla; Matthew Hess; Thomas Hilton; Chindanai Hongsaprabhas; Francis Hornicek; Keith Hosking; Eleanor Houghton; Oluwaseyi K. Idowu; Joseph Ippolito; Marc Isler; Shintaro Iwata; Jake Jagiello; Neil Jenkins; Thomas Jenkins; Charlotte Jeys; Tom Jeys; Luke Johnson; Andy Johnston; Min Wook Joo; Paul C. Jutte; Kadri Kaldas; Amar Kamat; Sudhir Kannan; Bilal Kapanci; Zeeshan Khan; Hiroshi Kobayashi; Yehuda Kollender; Sebastian Koob; Daniel Kotrych; Richard Kyte; Jose M. Lamo de Espinosa; Alexander L. Lazarides; Louis-Romee Le Nail; Pawel Legosz; Burkhard Lehner; Andreas Leithner; Maryse Lejoly; Valerae O. Lewis; Peng Lin; Francisco Linares; Santiago A. Lozano-Calderon; Ashish Mahendra; Ferdiansyah Mahyudin; Fermin J. Mandia Mancebo; Sara M. Torrejon; Christian Marx; Eric Mascard; Jean-Camille Mattei; Louise McCullough; Sam McMahon; Manuel R. Medellin Rincon; Benjamin Miller; Shinji Miwa; Gustavo Molina Uribe; Bryan Moon; Rhidian Morgan-Jones; Diego J. Moriel Garcesco; Carol Morris; Steward Morrison; Sophie Mottard; Marcio Moura; Linde Muster; Robert Nakayama; Prashant Narhari; Ana Navas; Prakash Nayak; Johannes Neugebauer; Erik T. Newman; Jyrki Nieminen; Emmy Nyqvist; Lukas Nystrom; Sarah O'Reilly-Harbidge; Gary O'Toole; Vania Oliveira; André Olivier; Mohamed Omar; Eduardo J. Ortiz-Cruz; Harzem Ozger; Korhan Ozkan; Elisa Pala; Emanuela Palmerini; Grant Pang; Panayiotis Papagelopoulos; Giovanni Paraliticci; Michael C. Parry; Sam Patton; David Peake; Ana Peiro Ibanez; Israel Perez Munoz; Ganapathy R. Perianayagam; Michael M. Petersen; Joris Ploegmakers; Robin Pollock; Gerard Powell; Juan Pretell; Jan Puetzler; Faisal Qamar; Anand Raja; Raja B. Rajasekaran; Dipak Ramkumar; R. L. Randall; Kenneth S. Rankin; Kevin A. Raskin; Kumaran Rassppan; Lauris Repsa; Mickael Ropars; Peter Rose; Wael Sadek; German Salcedo; Aasim Saleemi; Andrea Sambri; Hartej Sar; Roberto Scanferla; Thomas Schubert; Jan Schwarze; Guido Scoccianti; Ashley Scrimshire; Tetsuya Sekita; Ahmad Shehadeh; Ahmed Shoaib; Bhim Shreemal; Felix Shumelinsky; Geoffrey Siegel; Claudio Silveri; Robert Silverwood; Friedl Sinnaeve; Jerome Sison; Andrea Slade; Maria A. Smolle; Franz Snyman; Scott Sommerville; Sahil Sood; Andre Spiguel; Hugo St-Yves; Eric L. Staals; Silvia Stacchiotti; Nikolas Stavropoulos; Peter Steadman; Jonathan D. Stevenson; Mikaela Sullivan; Gwen Sys; Bartlomiej Szostakowski; Angela Tamburini; Yuta Taniguchi; Thomas Temple; Christoph Theil; Joachim Thorkildsen; Meagan Tibbo; Roger Tillman; Yu Toda; Kaspar Tootsi; Ferran Torner Rubies; Frank Traub; Ioannis Trikoupis; Panagiotis Tsagkozis; Kim Tsoi; Hiroyuki Tsuchiya; Veli-Matti Vainio; Antonio Valcarcel; Juan Valencia; Annelies Van Beeck; Michel Van de Sande; Thomas Van Den Berghe; Ingrid Van de Geest; Lizz Van der Heijden; Robert Van der Wal; Kirsten Van Langevelde; Gualter Vaz; Roberto Velez Villa; Floortje Verspoor; Koenraad Verstraete; Julia Visgauss; Oleg Vyrva; Hazem Wafa; Sebastian Walter; Wan F. Wan Ismail; Edward Wang; Patrick Q. Wang; David Warnock; Joel Werier; Wolfram Weschenfelder; Kwok-Chuen Wong; Marjan Woulthuyzen-Bakker; Jay Wunder; Indica Wysinghe; Norio Yamamoto; Zhaoming Ye; Seung-Jae Yoon; Suraya Zainul Abidin; Tomas Zamora; Pierluca Zecchetto; Liuzhe Zhang; Juan P. Zumarraga; Domenico A. Campanacci

doi:10.1302/0301-620X.107B2.BJJ-2024-0643.R1

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Identifying consensus and areas for future research in chondrosarcoma : a report from the Birmingham Orthopaedic Oncology Meeting

Journal article

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Peer reviewed

Identifying consensus and areas for future research in chondrosarcoma : a report from the Birmingham Orthopaedic Oncology Meeting

Lee M. Jeys, Guy V. Morris, Vineet J. Kurisunkal, Eduardo Botello, Richard A. Boyle, Walid Ebeid, Matthew T. Houdek, Ajay Puri, Pietro Ruggieri, Bernadette Brennan, …

The bone & joint journal, Vol.107-B(2), pp.246-252

2025

DOI: https://doi.org/10.1302/0301-620X.107B2.BJJ-2024-0643.R1

PMID: 39889743

Appears in Miller School of Medicine - Latest Publications

Abstract

Chondrosarcoma/therapy/diagnosis

Humans

Bone Neoplasms/therapy/diagnosis

Consensus

Orthopedics

Delphi Technique

AIMS: The Birmingham Orthopaedic Oncology Meeting (BOOM), held in January 2024, convened 309 delegates from 53 countries to discuss and refine 21 consensus statements on the optimal management of chondrosarcoma. METHODS: With representation from Europe (43%; n = 133), North America (17%; n = 53), South America (16%; n = 49), Asia (13%; n = 40), Australasia (5%; n = 16), the Middle East (4%; n = 12), and Africa (2%; n = 6), the combined experience of treating bone sarcomas among attendees totalled approximately 30,000 cases annually, equivalent to 66 years of experience in the UK alone. The meeting's process began with the formation of a local organizing committee, regional leads, and a scientific committee comprising representatives from 150 specialist units across 47 countries. Supported by major orthopaedic oncology organizations, the meeting used a modified Delphi process to develop consensus statements through online questionnaires, thematic groupings, narrative reviews, and anonymous pre-meeting polling. RESULTS: Strong (> 80%) consensus was achieved on 19 out of 21 statements, reflecting agreement among delegates. Key areas of consensus included the role of radiology in diagnosis and surveillance, the management of locally recurrent disease, and the treatment of dedifferentiated chondrosarcoma. Notably, there was agreement that routine chemotherapy has no role in chondrosarcoma treatment, and radiological surveillance is safe for intraosseous chondrosarcomas. Despite the overall consensus, areas of controversy remain, particularly regarding the treatment of atypical cartilage tumours and surgical margins. These unresolved issues underscore the need for further research and collaboration within the orthopaedic oncology community. CONCLUSION: BOOM represents the largest global consensus meeting in orthopaedic oncology, providing valuable guidance for clinicians managing chondrosarcoma worldwide. The consensus statements offer a reference for clinical practice, highlight key research priorities, and aim to improve patient outcomes on a global scale.

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Title: Identifying consensus and areas for future research in chondrosarcoma : a report from the Birmingham Orthopaedic Oncology Meeting
Creators: Lee M. Jeys - Royal Orthopaedic Hospital
Guy V. Morris - Royal Orthopaedic Hospital
Vineet J. Kurisunkal - Royal Orthopaedic Hospital
Eduardo Botello - Pontificia Universidad Católica de Chile
Richard A. Boyle - Royal Prince Alfred Hospital
Walid Ebeid - Cairo University
Matthew T. Houdek - Mayo Clinic
Ajay Puri - Homi Bhabha National Institute
Pietro Ruggieri - University of Padua
Bernadette Brennan - Royal Victoria Hospital
BOOM Consensus Meeting Participants
Minna K. Laitinen - Helsinki University Hospital
Santiago Abad Repiso
Hesham Abdelbary
Alejandro Abiad Mejia
Ahmed A. Abood
Juan C. Abril Martin
Adesegun Abudu
Ayman Abu Elhamd
Marthelena Acosta
Keisuke Ae
Manish Agarwal
Vivek Ajit Singh
Toru Akiyama
Ibrahim Alshaygy
Jose I. Albergo
John Alexander
Patricio A. Alfaro
Bugra Alpan
Jose Amaya-Valero
Megan Anderson
Dimosthenis Andreou
Lucas Annabell
Christopher Anthony
Ahmed Aoude
Iraia Arteagoitia-Colino
Apichat Asavamongkolkul
William Aston
Libe Asua Mentxaka
Christine Azzopardi
Thomas Baad-Hansen
Ismail T. Badr
Francisco Baixauli-Garcia
Gavin Baker
Tessa Balach
Giacomo G. Baldi
Janie Barry
Georges Basile
Stefano Bastoni
Mohammad Basuki
Henrik Bauer
Lee Bayliss
Ricardo G. Becker
Angad Bedi
Joseph Benevenia
Francisco Bengoa
Peter Bergh
Marko Bergovec
Nicholas Bernthal
Odion Binitie
David Boddie
Michele Boffano
Patricia Bonilla Huertas
Anna B. Borgognoni
Rajesh Botchu
Jos Bramer
Rahat Brar
Harriet Branford-White
Demien Broekhuis
Samuel E. Broida
Tymoteusz Budny
Zachary D. Burke
Jorge Cabrolier
Jose A. Calvo-Haro
Jorge R. Calvo Tapies
Rodrigo Cardoso
Richard Carey Smith
Pedro I. Carvallo
Nicolas Casales Fresenga
Jose M. Casanova
Oscar Ceballos
Juan L. Cebrian Parra
Sara Chacon Cartaya
Chung M. Chan
Yoon Joo Cho
Peter Choong
Yang-Guk Chung
Dawid Ciechanowicz
Miguel A. Clara-Altamirano
David Clever
Sebastian M. Colina
Luis Consuegra
Cory Couch
Gillian Cribb
Carlos Cuervo
Laurence A. Cusick
Solomon Dadia
Tanios Dagher
Dietmar Dammerer
Mark Davies
Nerys Davies
Luis P. de la Rosa Martino
Francisco J de Santos de la Fuente
Marieke de Vaal
Claudia Deckers
Javier Delgado Obando
Shaneel Deo
Niklas Deventer
Claudia Di Bella
Gregory Domson
Davide M. Donati
Desiree M. Dorleijn
Jacques Du Toit
Debra Dunne
Rodolfo Duran Ciarrochi
Elina Ekman
Ahmed M. El Ghoneimy
Makoto Endo
Levent Eralp
Mahmoud Etaiwi
Scott Evans
Robin Evrard
Will Eward
Alberto Farese
Peter C. Ferguson
Pedro F. Ferreira Cardoso
Fabrice Fiorenza
Michael Flint
Hector Flores
Joao Freitas
Bruno Fuchs
Tomohiro Fujiwara
Philipp T. Funovics
Marcos Galli Serra
Zakareya Gamie
Carlos Garces-Zarzalejo
Aaron Gazendam
Carsten Gebert
Jasper G. Gerbers
Craig Gerrand
Ghaith Abou-Nouar
Michelle Ghert
Kanishka M. Ghosh
Max Gibbons
Luis C. Gomez-Mier
Jesus Gomez-Vallejo
Anne Gomez-Mascard
Marcos R. Gonzalez
Fausto Gonzalez-Lizan
Georg Gosheger
Stuart Goudie
Krista Goulding
Stavros D. Goumenos
Anthony Griffin
Ashish Gulia
Sanjay Gupta
Amit Gupta
Maurice Guzman
Mohammed Haitham
Jendrik Hardes
Francisco Hardoy
Yusuf Hasan
Georg Hauer
Helard Havard
Rex Haydon
John Healey
Nerea Hernandez Gonzalez
Adriana Hernandez-Lopez
Asle Hesla
Matthew Hess
Thomas Hilton
Chindanai Hongsaprabhas
Francis Hornicek
Keith Hosking
Eleanor Houghton
Oluwaseyi K. Idowu
Joseph Ippolito
Marc Isler
Shintaro Iwata
Jake Jagiello
Neil Jenkins
Thomas Jenkins
Charlotte Jeys
Tom Jeys
Luke Johnson
Andy Johnston
Min Wook Joo
Paul C. Jutte
Kadri Kaldas
Amar Kamat
Sudhir Kannan
Bilal Kapanci
Zeeshan Khan
Hiroshi Kobayashi
Yehuda Kollender
Sebastian Koob
Daniel Kotrych
Richard Kyte
Jose M. Lamo de Espinosa
Alexander L. Lazarides
Louis-Romee Le Nail
Pawel Legosz
Burkhard Lehner
Andreas Leithner
Maryse Lejoly
Valerae O. Lewis
Peng Lin
Francisco Linares
Santiago A. Lozano-Calderon
Ashish Mahendra
Ferdiansyah Mahyudin
Fermin J. Mandia Mancebo
Sara M. Torrejon
Christian Marx
Eric Mascard
Jean-Camille Mattei
Louise McCullough
Sam McMahon
Manuel R. Medellin Rincon
Benjamin Miller
Shinji Miwa
Gustavo Molina Uribe
Bryan Moon
Rhidian Morgan-Jones
Diego J. Moriel Garcesco
Carol Morris
Steward Morrison
Sophie Mottard
Marcio Moura
Linde Muster
Robert Nakayama
Prashant Narhari
Ana Navas
Prakash Nayak
Johannes Neugebauer
Erik T. Newman
Jyrki Nieminen
Emmy Nyqvist
Lukas Nystrom
Sarah O'Reilly-Harbidge
Gary O'Toole
Vania Oliveira
André Olivier
Mohamed Omar
Eduardo J. Ortiz-Cruz
Harzem Ozger
Korhan Ozkan
Elisa Pala
Emanuela Palmerini
Grant Pang
Panayiotis Papagelopoulos
Giovanni Paraliticci
Michael C. Parry
Sam Patton
David Peake
Ana Peiro Ibanez
Israel Perez Munoz
Ganapathy R. Perianayagam
Michael M. Petersen
Joris Ploegmakers
Robin Pollock
Gerard Powell
Juan Pretell
Jan Puetzler
Faisal Qamar
Anand Raja
Raja B. Rajasekaran
Dipak Ramkumar
R. L. Randall
Kenneth S. Rankin
Kevin A. Raskin
Kumaran Rassppan
Lauris Repsa
Mickael Ropars
Peter Rose
Wael Sadek
German Salcedo
Aasim Saleemi
Andrea Sambri
Hartej Sar
Roberto Scanferla
Thomas Schubert
Jan Schwarze
Guido Scoccianti
Ashley Scrimshire
Tetsuya Sekita
Ahmad Shehadeh
Ahmed Shoaib
Bhim Shreemal
Felix Shumelinsky
Geoffrey Siegel
Claudio Silveri
Robert Silverwood
Friedl Sinnaeve
Jerome Sison
Andrea Slade
Maria A. Smolle
Franz Snyman
Scott Sommerville
Sahil Sood
Andre Spiguel
Hugo St-Yves
Eric L. Staals
Silvia Stacchiotti
Nikolas Stavropoulos
Peter Steadman
Jonathan D. Stevenson
Mikaela Sullivan
Gwen Sys
Bartlomiej Szostakowski
Angela Tamburini
Yuta Taniguchi
Thomas Temple
Christoph Theil
Joachim Thorkildsen
Meagan Tibbo
Roger Tillman
Yu Toda
Kaspar Tootsi
Ferran Torner Rubies
Frank Traub
Ioannis Trikoupis
Panagiotis Tsagkozis
Kim Tsoi
Hiroyuki Tsuchiya
Veli-Matti Vainio
Antonio Valcarcel
Juan Valencia
Annelies Van Beeck
Michel Van de Sande
Thomas Van Den Berghe
Ingrid Van de Geest
Lizz Van der Heijden
Robert Van der Wal
Kirsten Van Langevelde
Gualter Vaz
Roberto Velez Villa
Floortje Verspoor
Koenraad Verstraete
Julia Visgauss
Oleg Vyrva
Hazem Wafa
Sebastian Walter
Wan F. Wan Ismail
Edward Wang
Patrick Q. Wang
David Warnock
Joel Werier
Wolfram Weschenfelder
Kwok-Chuen Wong
Marjan Woulthuyzen-Bakker
Jay Wunder
Indica Wysinghe
Norio Yamamoto
Zhaoming Ye
Seung-Jae Yoon
Suraya Zainul Abidin
Tomas Zamora
Pierluca Zecchetto
Liuzhe Zhang
Juan P. Zumarraga
Domenico A. Campanacci
Publication Details: The bone & joint journal, Vol.107-B(2), pp.246-252
Publisher: Jeys et al; England
Number of pages: 7
Grant note: state for university-level research, Helsinki University Hospital, Finland: TYH 2023317
The open-access publication of this work was supported by funding from the state for university-level research, Helsinki University Hospital, Finland, under grant number TYH 2023317.
Comment: LR: 20250527; CI: © 2025; JID: 101599229; 2025/02/01 20:44 [medline]; 2025/02/01 20:43 [pubmed]; 2025/01/31 19:03 [entrez]; AID: BJJ-2024-0643.R1 [pii]; epublish
Academic Unit: Level 02 - Executives; Executives; UMMG Department of Orthopaedics; Miller School of Medicine; UMMG Dept of Orthopaedics - UHealth Sports Medicine; UMMG Dept of Medicine - Hematology/Oncology
Language: English
Resource Type: Journal article
PMID: 39889743
Record Identifier: 991032904109502976