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Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
Journal article   Open access  Peer reviewed

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Qian Zhang, Paul Bastard, Zhiyong Liu, Jérémie Le Pen, Marcela Moncada-Velez, Jie Chen, Masato Ogishi, Ira K D Sabli, Stephanie Hodeib, Cecilia Korol, …
Science (American Association for the Advancement of Science), Vol.370(6515), p.422
2020-10-23
PMID: 32972995

Abstract

Loss of Function Mutation Pandemics Humans Middle Aged Child, Preschool Infant Male Genetic Loci Interferon Regulatory Factor-7 - genetics Interferon Type I - immunology COVID-19 Young Adult Asymptomatic Infections SARS-CoV-2 Pneumonia, Viral - genetics Toll-Like Receptor 3 - deficiency Aged, 80 and over Betacoronavirus Adult Female Receptor, Interferon alpha-beta - genetics Toll-Like Receptor 3 - genetics Child Genetic Predisposition to Disease Receptor, Interferon alpha-beta - deficiency Coronavirus Infections - genetics Coronavirus Infections - immunology Pneumonia, Viral - immunology Interferon Regulatory Factor-7 - deficiency Adolescent Alleles Aged
url
https://doi.org/10.1126/science.abd4570View
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Citation topics
1 Clinical & Life Sciences
1.104 Virology - General
1.104.1353 Coronavirus
Web Of Science research areas
Immunology
ESI research areas
Immunology

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