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Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration
Journal article   Open access

Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration

A.M. Staffaroni, Y. Cobigo, S.-Y.M. Goh, J. Kornak, L. Bajorek, K. Chiang, B. Appleby, J. Bove, Y. Bordelon, P. Brannelly, …
Alzheimer's and Dementia, Vol.16(1), pp.37-48
2020
PMID: 31272932

Abstract

Atrophy Brain C9orf72 Protein Female Frontotemporal Dementia Genetic Predisposition to Disease Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging Male Middle Aged Mutation Neuropsychological Tests Progranulins tau Proteins biological marker grn protein guanine nucleotide exchange C9orf72 mapt protein unclassified drug C9orf72 protein, human GRN protein, human guanine nucleotide exchange C9orf72 MAPT protein, human tau protein adult aged Alzheimer disease amyotrophic lateral sclerosis Article asymptomatic disease brain atrophy Clinical Dementia Rating controlled study corticobasal degeneration cross validation diffuse Lewy body disease familial disease female follow up frontal variant frontotemporal dementia frontotemporal dementia gene mutation human image processing major clinical study male middle aged mild cognitive impairment onset age predictive value primary progressive aphasia priority journal progressive nonfluent aphasia risk assessment scoring system semantic dementia survival analysis symptom atrophy brain diagnostic imaging genetic predisposition genetics mutation neuropsychological test nuclear magnetic resonance imaging pathology
url
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065448095&doi=10.1016%2fj.jalz.2019.04.007&partnerID=40&md5=11699927b0371a12275f2b987a460ab5View
url
https://doi.org/10.1016/j.jalz.2019.04.007View
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