Intrasaccular flow disruption for ruptured aneurysms: an international multicenter study

Jose Danilo Bengzon Diestro; Mahmoud Dibas; Nimer Adeeb; Robert W Regenhardt; Justin E Vranic; Adrien Guenego; Sovann V Lay; Leonardo Renieri; Ali Al Balushi; Eimad Shotar; Kevin Premat; Kareem El Naamani; Guillaume Saliou; Markus A. Möhlenbruch; Ivan Lylyk; Paul M Foreman; Jay A Vachhani; Vedran Župančić; Muhammad U Hafeez; Caleb Rutledge; Hamid Rai; Vincent M Tutino; Shervin Mirshani; Sherief Ghozy; Pablo Harker; Naif M Alotaibi; James D Rabinov; Yifan Ren; Clemens M Schirmer; Oded Goren; Mariangela Piano; Anna Luisa Kuhn; Caterina Michelozzi; Stephanie Elens; Robert M Starke; Ameer Hassan; Arsalaan Salehani; Anh Nguyen; Jesse Jones; Marios Psychogios; Julian Spears; Carmen Parra-Fariñas; Maria Bres Bullrich; Michael Mayich; Mohamed M Salem; Jan-Karl Burkhardt; Brian T Jankowitz; Ricardo A Domingo; Thien Huynh; Rabih Tawk; Christian Ulfert; Boris Lubicz; Pietro Panni; Ajit S Puri; Guglielmo Pero; Christoph J Griessenauer; Hamed Asadi; Adnan Siddiqui; Andrew F Ducruet; Felipe C Albuquerque; Rose Du; Peter Kan; Vladimir Kalousek; Pedro Lylyk; Srikanth Reddy Boddu; Christopher J Stapleton; Jared Knopman; Pascal Jabbour; Stavropoula Tjoumakaris; Frédéric Clarençon; Nicola Limbucci; Mohammad A Aziz-Sultan; Hugo H Cuellar-Saenz; Christophe Cognard; Aman B Patel; Adam A Dmytriw

doi:10.1136/jnis-2022-019153

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Intrasaccular flow disruption for ruptured aneurysms: an international multicenter study

Journal article

Peer reviewed

Intrasaccular flow disruption for ruptured aneurysms: an international multicenter study

Jose Danilo Bengzon Diestro, Mahmoud Dibas, Nimer Adeeb, Robert W Regenhardt, Justin E Vranic, Adrien Guenego, Sovann V Lay, Leonardo Renieri, Ali Al Balushi, Eimad Shotar, …

Journal of neurointerventional surgery, Vol.15(9), pp.844-850

2023-09-01

DOI: https://doi.org/10.1136/jnis-2022-019153

PMID: 35868856

Appears in Miller School of Medicine - Latest Publications

Abstract

Aneurysm

New devices and techniques

BackgroundThe Woven EndoBridge (WEB) device is a novel intrasaccular flow disruptor tailored for bifurcation aneurysms. We aim to describe the degree of aneurysm occlusion at the latest follow-up, and the rate of complications of aneurysms treated with the WEB device stratified according to rupture status.MethodsOur data were taken from the WorldWideWeb Consortium, an international multicenter cohort including patients treated with the WEB device. Aneurysms were classified into two groups: ruptured and unruptured. We compared clinical and radiologic outcomes of both groups. Propensity score matching (PSM) was done to match according to age, gender, bifurcation, location, prior treatment, neck, height, dome width, daughter sac, incorporated branch, pretreatment antiplatelets, and last imaging follow-up.ResultsThe study included 676 patients with 691 intracranial aneurysms (529 unruptured and 162 ruptured) treated with the WEB device. The PSM analysis had 55 pairs. In both the unmatched (85.8% vs 84.3%, p=0.692) and matched (94.4% vs 83.3%, p=0.066) cohorts there was no significant difference in the adequate occlusion rate at the last follow-up. Likewise, there were no significant differences in both ischemic and hemorrhagic complications between the two groups. There was no documented aneurysm rebleeding after WEB device implantation.ConclusionThere was no significant difference in both the radiologic outcomes and complications between unruptured and ruptured aneurysms. Our findings support the feasibility of treatment of ruptured aneurysms with the WEB device.

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Title: Intrasaccular flow disruption for ruptured aneurysms: an international multicenter study
Creators: Jose Danilo Bengzon Diestro - St. Michael's Hospital
Mahmoud Dibas - Brigham and Women's Hospital
Nimer Adeeb - Louisiana State University in Shreveport
Robert W Regenhardt - Harvard University
Justin E Vranic - Massachusetts General Hospital
Adrien Guenego - Service de Neuroradiologie Interventionnelle, Hôpital Universitaire Erasme, Bruxelles, Belgique
Sovann V Lay - Hôpital Purpan
Leonardo Renieri - Interventistica Neurovascolare, Ospedale Careggi di Firenze, Florence, Italy
Ali Al Balushi - NewYork–Presbyterian Hospital
Eimad Shotar - Hôpital Charles-Foix
Kevin Premat - Hôpital Charles-Foix
Kareem El Naamani - Thomas Jefferson University
Guillaume Saliou - University Hospital of Lausanne
Markus A. Möhlenbruch - Heidelberg University
Ivan Lylyk - Equipo de Neurocirugía Endovascular y Radiología Intervencionista, Clínica La Sagrada Familia, Buenos Aires, Argentina
Paul M Foreman - Orlando Health
Jay A Vachhani - Orlando Health
Vedran Župančić - Sisters of Charity Hospital
Muhammad U Hafeez - Baylor School
Caleb Rutledge - Barrow Neurological Institute
Hamid Rai - University at Buffalo, State University of New York
Vincent M Tutino - University at Buffalo, State University of New York
Shervin Mirshani - Brigham and Women's Hospital
Sherief Ghozy - Mayo Clinic
Pablo Harker - Harvard University
Naif M Alotaibi - Massachusetts General Hospital
James D Rabinov - Massachusetts General Hospital
Yifan Ren - Austin Health
Clemens M Schirmer - Department of Neurosurgery, Geisinger, Wilkes-Barre, Pennsylvania, USA
Oded Goren - Geisinger Medical Center
Mariangela Piano - Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
Anna Luisa Kuhn - Memorial Hospital
Caterina Michelozzi - IRCCS Ospedale San Raffaele
Stephanie Elens - Service de Neuroradiologie Interventionnelle, Hôpital Universitaire Erasme, Bruxelles, Belgique
Robert M Starke - University of Miami
Ameer Hassan - Valley Baptist Medical Center
Arsalaan Salehani - University of Alabama at Birmingham
Anh Nguyen - University Hospital of Basel
Jesse Jones - University of Alabama at Birmingham
Marios Psychogios - University Hospital of Basel
Julian Spears - University of Toronto
Carmen Parra-Fariñas - University of Toronto
Maria Bres Bullrich - University of London
Michael Mayich - Western University
Mohamed M Salem - University of Pennsylvania
Jan-Karl Burkhardt - University of Pennsylvania
Brian T Jankowitz - University of Pennsylvania
Ricardo A Domingo - Mayo Clinic in Florida
Thien Huynh - Jacksonville College
Rabih Tawk - Mayo Clinic in Florida
Christian Ulfert - Heidelberg University
Boris Lubicz - Service de Neuroradiologie Interventionnelle, Hôpital Universitaire Erasme, Bruxelles, Belgique
Pietro Panni - IRCCS Ospedale San Raffaele
Ajit S Puri - Memorial Hospital
Guglielmo Pero - Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
Christoph J Griessenauer - Paracelsus Medical University
Hamed Asadi - Austin Health
Adnan Siddiqui - University at Buffalo, State University of New York
Andrew F Ducruet - Barrow Neurological Institute
Felipe C Albuquerque - Barrow Neurological Institute
Rose Du - Brigham and Women's Hospital
Peter Kan - Baylor School
Vladimir Kalousek - Sisters of Charity Hospital
Pedro Lylyk - Equipo de Neurocirugía Endovascular y Radiología Intervencionista, Clínica La Sagrada Familia, Buenos Aires, Argentina
Srikanth Reddy Boddu - New York Hospital Queens
Christopher J Stapleton - Massachusetts General Hospital
Jared Knopman - New York Hospital Queens
Pascal Jabbour - Thomas Jefferson University
Stavropoula Tjoumakaris - Thomas Jefferson University
Frédéric Clarençon - Hôpital Charles-Foix
Nicola Limbucci - Interventistica Neurovascolare, Ospedale Careggi di Firenze, Florence, Italy
Mohammad A Aziz-Sultan - Brigham and Women's Hospital
Hugo H Cuellar-Saenz - Louisiana State University
Christophe Cognard - Hôpital Purpan
Aman B Patel - Harvard University
Adam A Dmytriw - Massachusetts General Hospital
Publication Details: Journal of neurointerventional surgery, Vol.15(9), pp.844-850
Publisher: BMJ Publishing Group Ltd
Academic Unit: UMMG Dept of Neurological Surgery; Miller School of Medicine
Language: English
Resource Type: Journal article
PMID: 35868856
Record Identifier: 991032796357102976