Kinase Dead BTK Mutations Confer Resistance to Covalent and Noncovalent BTK Inhibitors but Are Susceptible to Clinical Stage BTK Degraders

Skye Montoya; Jessie Bourcier; Meghan C. Thompson; Mark Noviski; May Tan; Eric Wang; Xiaoli Mi; Nivetha Brathaban; Carla Barrientos Risso; Daniel Tsai; Jordan Ye; Jacob Jahn; Gabriel Pardo; Lee Cabuhat; Ryan Notti; Alejandro Pardo; Maurizio Affer; Stephanie Yung; James Luliano; Janine Powers; Daniel W Robbins; Vindhya Nawaratne; Tulasigeri M Totiger; Camila Pena-Velasquez; Joanna M. Rhodes; Andrew D. Zelenetz; Lindsey E. Roeker; Hao Lu; Adam Linley; Anthony R. Mato; Omar Abdel-Wahab; Justin Taylor

doi:10.1182/blood-2022-163268

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Kinase Dead BTK Mutations Confer Resistance to Covalent and Noncovalent BTK Inhibitors but Are Susceptible to Clinical Stage BTK Degraders

Journal article

Peer reviewed

Kinase Dead BTK Mutations Confer Resistance to Covalent and Noncovalent BTK Inhibitors but Are Susceptible to Clinical Stage BTK Degraders

Skye Montoya, Jessie Bourcier, Meghan C. Thompson, Mark Noviski, May Tan, Eric Wang, Xiaoli Mi, Nivetha Brathaban, Carla Barrientos Risso, Daniel Tsai, …

Blood, Vol.140(Supplement 1), pp.1811-1813

2022-11-15

DOI: https://doi.org/10.1182/blood-2022-163268

Appears in Miller School of Medicine - Latest Publications

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.130 Lymphomas; 1.130.1170 Chronic Lymphocytic Leukemia
Web Of Science research areas: Hematology
ESI research areas: Clinical Medicine

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Title: Kinase Dead BTK Mutations Confer Resistance to Covalent and Noncovalent BTK Inhibitors but Are Susceptible to Clinical Stage BTK Degraders
Creators: Skye Montoya - Sylvester Comprehensive Cancer Center
Jessie Bourcier - Memorial Sloan Kettering Cancer Center
Meghan C. Thompson - Memorial Sloan Kettering Cancer Center
Mark Noviski - Nurix
May Tan - Nurix
Eric Wang - Memorial Sloan Kettering Cancer Center
Xiaoli Mi - Memorial Sloan Kettering Cancer Center
Nivetha Brathaban - Nurix
Carla Barrientos Risso - University of Miami
Daniel Tsai - University of Miami
Jordan Ye - Nurix
Jacob Jahn - Sylvester Comprehensive Cancer Center
Gabriel Pardo - Sylvester Comprehensive Cancer Center
Lee Cabuhat - Nurix
Ryan Notti - Rockefeller University
Alejandro Pardo - Sylvester Comprehensive Cancer Center
Maurizio Affer - University of Miami
Stephanie Yung - Nurix
James Luliano - Nurix
Janine Powers - Nurix
Daniel W Robbins - Nurix
Vindhya Nawaratne - Sylvester Comprehensive Cancer Center
Tulasigeri M Totiger - University of Miami
Camila Pena-Velasquez - Memorial Sloan Kettering Cancer Center
Joanna M. Rhodes - Northwell Health
Andrew D. Zelenetz - Memorial Sloan Kettering Cancer Center
Lindsey E. Roeker - Memorial Sloan Kettering Cancer Center
Hao Lu - Nurix
Adam Linley - University of Liverpool
Anthony R. Mato - Memorial Sloan Kettering Cancer Center
Omar Abdel-Wahab - Memorial Sloan Kettering Cancer Center
Justin Taylor - Sylvester Comprehensive Cancer Center
Publication Details: Blood, Vol.140(Supplement 1), pp.1811-1813
Publisher: Elsevier Inc; AMSTERDAM
Number of pages: 3
Academic Unit: Miller School of Medicine; UMMG Dept of Medicine - Hematology/Oncology; Sylvester Comprehensive Cancer Center
Language: English
Resource Type: Journal article
Record Identifier: 991032860865002976