Lessons from Recent Phase III Trial Failures: Don't Design Phase III Trials Based on Retrospective Subgroup Analyses from Phase II Trials

Journal article

Peer reviewed

Philip J Rosenfeld and William J Feuer

Ophthalmology (Rochester, Minn.), Vol.125(10), pp.1488-1491

2018-10

PMID: 30243330

Abstract

Vascular Endothelial Growth Factor A

Retrospective Studies

Research Design

Humans

Macular Degeneration

2 Record Views

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Citation topics: 1 Clinical & Life Sciences; 1.155 Medical Ethics; 1.155.611 Evidence Based Medicine
Web Of Science research areas: Ophthalmology
ESI research areas: Clinical Medicine

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Title: Lessons from Recent Phase III Trial Failures: Don't Design Phase III Trials Based on Retrospective Subgroup Analyses from Phase II Trials
Creators: Philip J Rosenfeld - Miami, Florida. Electronic address: prosenfeld@med.miami.edu
William J Feuer - Miami, Florida
Publication Details: Ophthalmology (Rochester, Minn.), Vol.125(10), pp.1488-1491
Academic Unit: Miller School of Medicine; UMMG Department of Ophthalmology
Language: English
Resource Type: Journal article
PMID: 30243330
Record Identifier: 991031598264702976