Abstract
New medication treatments for HIV have recently improved so that survival over long periods is now possible, but these treatment gains are wholly dependent on proper use of the medications. Improper use of medications, missed or delayed doses, or drug holidays from part of the treatment regimen may be as deleterious as no medications at all. Despite its importance, the number of medications, complex dosage schedules, and significant side-effect profiles of these medications makes adherence to HIV medications difficult. This paper describes a new cognitive-behavioral intervention in which education, problem solving, and rehearsal strategies are used to help patients develop better skills for adhering to HIV treatment.