Abstract
To describe a previously unreported electroretinographic (ERG) pattern in early retinitis pigmentosa (RP).
Two case reports.
Two unrelated young asymptomatic patients with autosomal-dominant retinitis pigmentosa were studied.
Clinical findings and ERG responses were assessed.
No ERG responses were detected scotopically with low-luminance stimuli. With increasingly brighter stimuli, a series of three to five low-frequency damped wavelets developed under both scotopic and photopic conditions. The period of the wavelets was 25 to 37 msec.
Low-frequency damped ERG wavelets occur in some young asymptomatic patients with autosomal-dominant RP. The ERG pattern suggests that these wavelets are predominantly cone-generated.
