Abstract
The management of patients with metastatic disease of the humerus is a complex and challenging problem. Patients present with varying degrees of bone destruction and medical debilitation. The pattern of metastatic disease spread, with frequent involvement of the lower extremity, especially the proximal femur, often places increased functional demands on the upper extremity for mobility. Optimal treatment requires coordination between the orthopedic surgeon, pathologist, medical oncologist, and radiation oncologist along with close communication with the patient and patient's family to develop a course of treatment that results in pain relief and improved function.