Maastricht Delphi consensus on event definitions for classification of recurrence in breast cancer research

Martine Moossdorff; Lori M van Roozendaal; Luc J A Strobbe; Stefan Aebi; David A Cameron; J Michael Dixon; Armando E Giuliano; Bruce G Haffty; Brigid E Hickey; Clifford A Hudis; V Suzanne Klimberg; Bogda Koczwara; Thorsten Kühn; Marc E Lippman; Anthony Lucci; Martine Piccart; Benjamin D Smith; Vivianne C G Tjan-Heijnen; Cornelis J H van de Velde; Kimberly J Van Zee; Jan B Vermorken; Giuseppe Viale; Adri C Voogd; Irene L Wapnir; Julia R White; Marjolein L Smidt

doi:10.1093/jnci/dju288

Back

Maastricht Delphi consensus on event definitions for classification of recurrence in breast cancer research

Journal article

Open access

Maastricht Delphi consensus on event definitions for classification of recurrence in breast cancer research

Martine Moossdorff, Lori M van Roozendaal, Luc J A Strobbe, Stefan Aebi, David A Cameron, J Michael Dixon, Armando E Giuliano, Bruce G Haffty, Brigid E Hickey, Clifford A Hudis, …

JNCI : Journal of the National Cancer Institute, Vol.106(12), p.1

2014-12

DOI: https://doi.org/10.1093/jnci/dju288

PMCID: PMC4357796

PMID: 25381395

Abstract

Humans

Carcinoma, Intraductal, Noninfiltrating - diagnosis

International Cooperation

Lymphatic Metastasis

Neoplasm Recurrence, Local - diagnosis

Neoplasms, Second Primary - diagnosis

Neoplasm Recurrence, Local - pathology

Delphi Technique

Breast Neoplasms - pathology

Skin Neoplasms - secondary

Female

Surveys and Questionnaires

Breast Neoplasms - diagnosis

Neoplasms, Second Primary - pathology

Thoracic Wall - pathology

In breast cancer studies, many different endpoints are used. Definitions are often not provided or vary between studies. For instance, "local recurrence" may include different components in similar studies. This limits transparency and comparability of results. This project aimed to reach consensus on the definitions of local event, second primary breast cancer, regional and distant event for breast cancer studies. The RAND-UCLA Appropriateness method (modified Delphi method) was used. A Consensus Group of international breast cancer experts was formed, including representatives of all involved clinical disciplines. Consensus was reached in two rounds of online questionnaires and one meeting. Twenty-four international breast cancer experts participated. Consensus was reached on 134 items in four categories. Local event is defined as any epithelial breast cancer or ductal carcinoma in situ (DCIS) in the ipsilateral breast, or skin and subcutaneous tissue on the ipsilateral thoracic wall. Second primary breast cancer is defined as epithelial breast cancer in the contralateral breast. Regional events are breast cancer in ipsilateral lymph nodes. A distant event is breast cancer in any other location. Therefore, this includes metastasis in contralateral lymph nodes and breast cancer involving the sternal bone. If feasible, tissue sampling of a first, solitary, lesion suspected for metastasis is highly recommended. This project resulted in consensus-based event definitions for classification of recurrence in breast cancer research. Future breast cancer research projects should adopt these definitions to increase transparency. This should facilitate comparison of results and conducting reviews as well as meta-analysis.

Files and links (1)

url

https://doi.org/10.1093/jnci/dju288View

Published (Version of record) Open

Metrics

9 Record Views

60 Times Cited - Web of Science

See more details

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.119 Breast Cancer Scanning; 1.119.574 Lymphedema
Web Of Science research areas: Oncology
ESI research areas: Clinical Medicine

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

Source: InCites

Details

Title: Maastricht Delphi consensus on event definitions for classification of recurrence in breast cancer research
Creators: Martine Moossdorff - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Lori M van Roozendaal - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Luc J A Strobbe - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Stefan Aebi - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
David A Cameron - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
J Michael Dixon - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Armando E Giuliano - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Bruce G Haffty - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Brigid E Hickey - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Clifford A Hudis - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
V Suzanne Klimberg - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Bogda Koczwara - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Thorsten Kühn - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Marc E Lippman - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Anthony Lucci - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Martine Piccart - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Benjamin D Smith - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Vivianne C G Tjan-Heijnen - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Cornelis J H van de Velde - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Kimberly J Van Zee - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Jan B Vermorken - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Giuseppe Viale - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Adri C Voogd - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Irene L Wapnir - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Julia R White - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Marjolein L Smidt - Department of Surgery and GROW School for Oncology and Developmental Biology (MM, MLS), Department of Surgery and Radiology (LMvR), Department of Medical Oncology, GROW School for Oncology and Developmental Biology (VCGTH), and Department of Epidemiology and GROW School for Oncology and Developmental Biology (ACV), Maastricht University Medical Center, Maastricht, the Netherlands; Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (LJAS); Division of Medical Oncology, Luzerner Kantonsspital, Lucerne, Switzerland (SA); Edinburgh Cancer Research Centre, University of Edinburgh and NHS Lothian (DAC), Edinburgh Breast Unit (JMD), Western General Hospital, Edinburgh, UK; Cedars-Sinai Medical Center, Los Angeles, CA (AEG); Rutgers Cancer Institute of New Jersey, New Brunswick, NJ (BGH); Mater Centre Radiation Oncology Service, Princess Alexandra Hospital, Brisbane, Australia (BEH); Breast Cancer Medicine Service, Memorial Sloan Kettering Cancer Center and Professor of Medicine, Weill Cornell Medical College, New York, NY (CAH); University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, Little Rock, AR (VSK); Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, Australia (BK); Interdisciplinary Breast Centre, Department of Gynaecology and Obstetrics, Klinikum Esslingen, Germany (TK); University of Miami Miller School of Medicine, Miami, FL (MEL); Radiation Oncology (BDS) and Department of Surgical Oncology, Division of Surgery (AL), University of Texas/MD Anderson Cancer Center, Houston, TX; Institut Jules Bordet, Université Libre de Bruxelles, Head of Medicine Department, Brussels, Belgium (MP); Surgery, University Medical Center, Leiden, the Netherlands (CJHvdV); Breast Service, Memorial Sloan-Kettering Cancer Center, Evelyn Lauder Breast Center, New York, NY(KJVZ); Antwerp University Hospital, Department of Medical Oncology, Edegem, Belgium (JBV); Department of Pathology, European Institute of
Publication Details: JNCI : Journal of the National Cancer Institute, Vol.106(12), p.1
Publisher: United States
Grant note: P30 CA008748 / NCI NIH HHS P30 CA016672 / NCI NIH HHS
Academic Unit: Miller School of Medicine; UMMG Dept of Medicine - Hematology/Oncology
Language: English
Resource Type: Journal article
PMID: 25381395
PMCID: PMC4357796
Record Identifier: 991031578633802976