Abstract
•General population dosing can guide psychotropic medication prescribing in epilepsy.•We present general dosing of antidepressants, stimulants, and common antipsychotics.•Common side effects of psychotropic medications are listed.•Interactions of antiseizure medications with psychotropic medications are presented.•Psychotropic and cognitive properties of antiseizure medications are outlined.
Many psychotropic medications are prescribed to people with epilepsy by neurologists and other non-neurology providers. This article presents summary tables with information on specific psychotropic drug classes (antidepressants, stimulant medications, and antipsychotic medications) including initiation schedules, dosing and indication. Given the overall paucity of epilepsy specific data available, the information is based primarily on regulatory approvals or other general population data, along with unique considerations for epilepsy such as interactions with antiseizure medications. While information is presented across the age span for antidepressants and stimulants, information on antipsychotic medications is focused on the most commonly prescribed medications for adults with psychotic episodes or acutely agitated states. Summary information on psychiatric and cognitive side effects of antiseizure medications and psychotropic benefits of antiseizure medications are also presented. This article is intended to provide a handy reference to neurologists involved in managing mental health in a clinical setting or caring for patients already receiving psychotropic medication treatment for mental health comorbidities. This article provides an overview of a more comprehensive list of psychotropic medications than the case-based articles of the special issue and is intended to supplement the focused and practical information presented in the other articles.