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Multiple γc-dependent cytokines regulate T-cell development
Journal article

Multiple γc-dependent cytokines regulate T-cell development

Thomas R Malek, Brian O Porter and You-Wen He
Immunology today (Amsterdam. Regular ed.), Vol.20(2), pp.71-76
1999
DOI: https://doi.org/10.1016/S0167-5699(98)01391-7
PMID: 10098325

Abstract

Interleukin 7 X-linked severe combined immunodeficiency Cytokine X-SCID T-cell development gc chain IL-7
Mutations in the common γ chain (γc) of cytokine receptors account for human X-linked severe combined immunodeficiency disease. γc contributes to ligand binding and signaling as a component of five cytokine receptors: interleukin-2-receptor (IL-2R), IL-4R, IL-7R, IL-9R and IL-15R. Here, Thomas Malek and colleagues discuss the contribution of individual γc-dependent cytokines in both conventional and intraepithelial T-cell development.

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58 Times Cited - Web of Science

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Collaboration types
Domestic collaboration
Citation topics
1 Clinical & Life Sciences
1.6 Immunology
1.6.127 T Cell Receptor
Web Of Science research areas
Immunology
ESI research areas
Immunology

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#3 Good Health and Well-Being

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