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Neural abnormalities in the dystrophic mouse
Journal article   Peer reviewed

Neural abnormalities in the dystrophic mouse

W G Bradley and M Jenkison
Journal of the neurological sciences, Vol.25(2), pp.249-255
1975-06
DOI: https://doi.org/10.1016/0022-510X(75)90144-6
PMID: 1151435

Abstract

Muscular Dystrophy, Animal - genetics Myelin Sheath - pathology Sciatic Nerve - pathology Microscopy, Electron Muscular Dystrophy, Animal - pathology Peripheral Nerves - pathology Spinal Nerve Roots - ultrastructure Animals Schwann Cells - ultrastructure Cranial Nerves - pathology Mice Myelin Sheath - ultrastructure Spinal Nerve Roots - pathology
Neural abnormalities (area of amyelination) have been found in the cranial nerves and in the ventral cervical and lumbosacral roots and in the mixed spinal nerves of bar harbor dystrophic mice of both the severe (129 Re/J dy/dy) and benign (dy-2J DY-2J) forms. The significance of these findings is discussed.

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