ORAL ABSTRACT: CLL-563 Bexobrutideg (NX-5948), a Novel Bruton’s Tyrosine Kinase Degrader, Demonstrates Rapid and Durable Clinical Responses in Relapsed/Refractory Chronic Lymphocytic Leukemia: Updated Findings from an Ongoing Phase 1a Study

Zulfa Omer; Alexey Danilov; Francesco Forconi; Nirav Shah; Graham P. Collins; Shuo Ma; Jane Robertson; Alvaro Alencar; Danielle Brander; John C. Byrd; Dima El-Sharkawi; Jeffery Smith; Allison Winter; Michal Kwiatek; Jonathon Cohen; Prioty Islam; Sarah Injac; Talha Munir

doi:10.1016/S2152-2650(25)00374-X

$ORAL ABSTRACT: CLL-563 Bexobrutideg (NX-5948), a Novel Bruton’s Tyrosine Kinase Degrader, Demonstrates Rapid and Durable Clinical Responses in Relapsed/Refractory Chronic Lymphocytic Leukemia: Updated Findings from an Ongoing Phase 1a Study$

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ORAL ABSTRACT: CLL-563 Bexobrutideg (NX-5948), a Novel Bruton’s Tyrosine Kinase Degrader, Demonstrates Rapid and Durable Clinical Responses in Relapsed/Refractory Chronic Lymphocytic Leukemia: Updated Findings from an Ongoing Phase 1a Study

Zulfa Omer, Alexey Danilov, Francesco Forconi, Nirav Shah, Graham P. Collins, Shuo Ma, Jane Robertson, Alvaro Alencar, Danielle Brander, John C. Byrd, …

Clinical lymphoma, myeloma and leukemia, Vol.25, pp.S163-S163

2025-09

DOI: https://doi.org/10.1016/S2152-2650(25)00374-X

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Title: ORAL ABSTRACT: CLL-563 Bexobrutideg (NX-5948), a Novel Bruton’s Tyrosine Kinase Degrader, Demonstrates Rapid and Durable Clinical Responses in Relapsed/Refractory Chronic Lymphocytic Leukemia: Updated Findings from an Ongoing Phase 1a Study
Creators: Zulfa Omer - University of Cincinnati
Alexey Danilov - City Of Hope National Medical Center
Francesco Forconi - University Hospital Southampton NHS Foundation Trust
Nirav Shah - Medical College of Wisconsin
Graham P. Collins - Churchill Hospital
Shuo Ma - Northwestern University
Jane Robertson - Cancer Research UK Manchester Centre
Alvaro Alencar - University of Miami
Danielle Brander - Duke Cancer Institute
John C. Byrd - University of Cincinnati
Dima El-Sharkawi - Royal Marsden NHS Foundation Trust
Jeffery Smith - The Clatterbridge Cancer Centre, Liverpool, United Kingdom
Allison Winter - Cleveland Clinic
Michal Kwiatek - AidPort Hospital, Skórzewo (Poznan), Poland
Jonathon Cohen - Winship Cancer Institute
Prioty Islam - Memorial Sloan Kettering Cancer Cancer, New York, NY, USA
Sarah Injac - Nurix
Talha Munir - St. James's Hospital
Publication Details: Clinical lymphoma, myeloma and leukemia, Vol.25, pp.S163-S163
Publisher: Elsevier Inc
Academic Unit: Miller School of Medicine; UMMG Dept of Medicine - Hematology/Oncology
Language: English
Resource Type: Journal article
Record Identifier: 991032787229402976