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Off-Target V(D)J Recombination Drives Lymphomagenesis and Is Escalated by Loss of the Rag2 C Terminus
Journal article   Open access  Peer reviewed

Off-Target V(D)J Recombination Drives Lymphomagenesis and Is Escalated by Loss of the Rag2 C Terminus

Martina Mijušković, Yi-Fan Chou, Vered Gigi, Cory R Lindsay, Olga Shestova, Susanna M Lewis and David B Roth
Cell reports (Cambridge), Vol.12(11), pp.1842-1852
2015-09-22
PMCID: PMC5089067
PMID: 26365182

Abstract

Tumor Suppressor Proteins - metabolism Mice, Inbred C57BL V(D)J Recombination Lymphoma - genetics Thymus Neoplasms - genetics DNA-Binding Proteins - genetics Thymus Neoplasms - metabolism DNA-Binding Proteins - metabolism Lymphoma - metabolism Animals Tumor Suppressor Proteins - genetics Mice Disease Models, Animal
url
https://doi.org/10.1016/j.celrep.2015.08.034View
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Collaboration types
Domestic collaboration
International collaboration
Citation topics
1 Clinical & Life Sciences
1.6 Immunology
1.6.452 Somatic Hypermutation
Web Of Science research areas
Cell Biology
ESI research areas
Molecular Biology & Genetics

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