Opening the Chromatin by eRNAs

Ramin Shiekhattar

doi:10.1016/j.molcel.2013.08.033

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Journal article

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Peer reviewed

Opening the Chromatin by eRNAs

Ramin Shiekhattar

Molecular cell, Vol.51(5), pp.557-558

2013-09-12

DOI: https://doi.org/10.1016/j.molcel.2013.08.033

PMCID: PMC4492513

PMID: 24034693

Abstract

Chromatin - metabolism

Enhancer Elements, Genetic - genetics

MyoD Protein - metabolism

Animals

Myogenin - metabolism

RNA - metabolism

Enhancer RNAs (eRNAs) have emerged as an important component of transcriptional activation. In this issue, Mousavi et al. (2013) have uncovered a critical role for eRNAs in regulation of myogenic differentiation program through increasing chromatin accessibility at MyoD and MyoG loci.

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Citation topics: 1 Clinical & Life Sciences; 1.54 Molecular & Cell Biology - Genetics; 1.54.100 DNA Methylation
Web Of Science research areas: Biochemistry & Molecular Biology; Cell Biology
ESI research areas: Molecular Biology & Genetics

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Details

Title: Opening the Chromatin by eRNAs
Creators: Ramin Shiekhattar - The Wistar Institute, Philadelphia, PA 19104, USA. Electronic address: shiekhattar@wistar.org
Publication Details: Molecular cell, Vol.51(5), pp.557-558
Grant note: R01 GM105754 / NIGMS NIH HHS
Academic Unit: Miller School of Medicine; UMMG Dept of Human Genetics - Clinical and Translational Genetics; UMMG Dept of Human Genetics (Dr. John T. Macdonald Foundation)
Language: English
Resource Type: Journal article
PMID: 24034693
PMCID: PMC4492513
Record Identifier: 991031597981702976