Potential application of a chemically modified non-antimicrobial tetracycline (CMT-3) against metastatic prostate cancer

Journal article

B L Lokeshwar, H L Houston-Clark, M G Selzer, N L Block and L M Golub

Advances in dental research, Vol.12(2), pp.97-102

1998-11

PMID: 9972130

Abstract

Lung Neoplasms - drug therapy

Tetracyclines - chemistry

Apoptosis - drug effects

Epithelial Cells - drug effects

Humans

Male

Tetracyclines - pharmacology

Anti-Inflammatory Agents, Non-Steroidal - pharmacology

Anti-Bacterial Agents - therapeutic use

Protease Inhibitors - pharmacology

Neoplasm Metastasis

Drug Interactions

Lung Neoplasms - secondary

Metalloendopeptidases - antagonists & inhibitors

Prostatic Neoplasms - pathology

Lung Neoplasms - enzymology

Doxycycline - therapeutic use

Tumor Cells, Cultured - drug effects

Rats

Cell Division - drug effects

Regression Analysis

Animals

Prostatic Neoplasms - enzymology

Doxycycline - pharmacology

Anti-Bacterial Agents - pharmacology

Flurbiprofen - pharmacology

Tetracyclines - therapeutic use

12 Record Views

Title: Potential application of a chemically modified non-antimicrobial tetracycline (CMT-3) against metastatic prostate cancer
Creators: B L Lokeshwar - Department of Urology, University of Miami School of Medicine, Florida 33101, USA
H L Houston-Clark
M G Selzer
N L Block
L M Golub
Publication Details: Advances in dental research, Vol.12(2), pp.97-102
Publisher: United States
Grant note: CA 63108-R29 / NCI NIH HHS
Academic Unit: UMMG Department of Pathology; UMMG Department of Urology
Language: English
Resource Type: Journal article
PMID: 9972130
Record Identifier: 991031561143202976