Abstract
The prevalence of Prolonged Grief Disorder has ranged from 7% to 65% in different samples depending on the severity of the grief experience. A narrative review of the current literature (2024-2025) on Prolonged Grief Disorder has yielded papers on negative effects, risk factors, potential underlying biological mechanisms and interventions. The negative effects include loneliness, poor quality of life, depression, PTSD, psychosis and broken heart syndrome. The risk factors have included anxious attachment, rumination, anxiety, PTSD, insomnia, COVID, earthquake, terror, and relationship to the deceased. The potential underlying biological mechanisms have included oxytocin dysfunction and involvement of the nucleus accumbens (the reward region of the brain). Cognitive behavioral therapy has been the most frequently researched intervention.