Sign in
Back
Protein-protein interactions in eukaryotic transcription initiation : structure of the preinitiation complex
Journal article   Peer reviewed

Protein-protein interactions in eukaryotic transcription initiation : structure of the preinitiation complex

Hong Tang, Xiaoqing Sun, Danny Reinberg and Richard H. Ebright
Proceedings of the National Academy of Sciences of the United States of America, Vol.93(3), pp.1119-1124
1996
DOI: https://doi.org/10.1073/pnas.93.3.1119

Abstract

We have used alanine scanning to analyze protein-protein interactions by human TATA-element binding protein (TBP) within the transcription preinitiation complex. The results indicate that TBP interacts with RNA polymerase II and general transcription factors IIA, IIB, and IIF within the functional transcription preinitiation complex and define the determinants of TBP for each of these interactions. The results permit construction of a model for the structure of the preinitiation complex.
url
https://lens.org/070-733-099-732-516View
url
https://www.pnas.org/content/pnas/93/3/1119.full.pdfView
url
https://www.pnas.org/content/93/3/1119.full.pdfView
url
http://europepmc.org/articles/PMC40041View
url
https://www.ncbi.nlm.nih.gov/pubmed/8577725View

Metrics

1 Record Views

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types
Domestic collaboration
Citation topics
1 Clinical & Life Sciences
1.42 Bacteriology
1.42.131 RNA Polymerase
Web Of Science research areas
Biochemistry & Molecular Biology
ESI research areas
Biology & Biochemistry

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

Source: InCites

Details