Abstract
The microbiome is important to the host as a whole, both in maintenance of health and in the pathophysiology of disease. The purpose of this review is to explore the relationship between the gut, ocular microbiome, and ocular disease states. We will also discuss how the microbiome can serve as a potential target for treatment, by methods such as modulation of diet, probiotics and fecal microbiota transplantation. The information discussed in the review has been gathered using literature published from 2004 to November 2018, as indexed in PubMed.
•Dysbiosis refers to shifts or changes of the microbiome.•There are links between disease states and dysbiosis of both the gut and ocular surface.•The ocular and gut microbiomes may be future targets for treatment in a variety of diseases.