Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response

Vanessa E ZANNELLA; Alan DAL PRA; Bradly G WOUTERS; Robert G BRISTOW; Marianne KORITZINSKY; Hala MUADDI; Trevor D MCKEE; Shawn STAPLETON; Jenna SYKES; Rachel GLICKSMAN; Selim CHAIB; Paul ZAMIARA; Michael MILOSEVIC

doi:10.1158/1078-0432.CCR-13-1787

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Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response

Journal article

Open access

Peer reviewed

Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response

Vanessa E ZANNELLA, Alan DAL PRA, Bradly G WOUTERS, Robert G BRISTOW, Marianne KORITZINSKY, Hala MUADDI, Trevor D MCKEE, Shawn STAPLETON, Jenna SYKES, Rachel GLICKSMAN, …

Clinical cancer research, Vol.19(24), pp.6741-6750

2013

DOI: https://doi.org/10.1158/1078-0432.CCR-13-1787

PMID: 24141625

Abstract

Biological and medical sciences

Multiple tumors. Solid tumors. Tumors in childhood (general aspects)

Medical sciences

Antineoplastic agents

Pharmacology. Drug treatments

Tumors

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https://doi.org/10.1158/1078-0432.CCR-13-1787View

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243 Times Cited - Web of Science

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Highly Cited Paper

Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.26 Diabetes; 1.26.1418 Metformin
Web Of Science research areas: Oncology
ESI research areas: Clinical Medicine

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Details

Title: Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response
Creators: Vanessa E ZANNELLA - Princess Margaret Cancer Centre, University Health Network, Canada
Alan DAL PRA - Princess Margaret Cancer Centre, University Health Network, Canada
Bradly G WOUTERS - Princess Margaret Cancer Centre, University Health Network, Canada
Robert G BRISTOW - Princess Margaret Cancer Centre, University Health Network, Canada
Marianne KORITZINSKY - Princess Margaret Cancer Centre, University Health Network, Canada
Hala MUADDI - Princess Margaret Cancer Centre, University Health Network, Canada
Trevor D MCKEE - Princess Margaret Cancer Centre, University Health Network, Canada
Shawn STAPLETON - Princess Margaret Cancer Centre, University Health Network, Canada
Jenna SYKES - Princess Margaret Cancer Centre, University Health Network, Canada
Rachel GLICKSMAN - Radiation Medicine Program, University Health Network, Canada
Selim CHAIB - Princess Margaret Cancer Centre, University Health Network, Canada
Paul ZAMIARA - Princess Margaret Cancer Centre, University Health Network, Canada
Michael MILOSEVIC - Princess Margaret Cancer Centre, University Health Network, Canada
Publication Details: Clinical cancer research, Vol.19(24), pp.6741-6750
Publisher: American Association for Cancer Research
Academic Unit: Miller School of Medicine; UMMG Dept of Radiation Oncology
Language: English
Resource Type: Journal article
PMID: 24141625
Record Identifier: 991031598253902976