Abstract
We report the case of a 16-year-old girl from Central Africa who was hospitalized with an acute vasoclusive crisis and lumbar pain. She had a medical history of malaria at 6 years of age, yellow fever at 14, sickle cell disease at 2, and hepatopathy by hepatitis C virus. Splenic ultrasound revealed splenic enlargement with multiple hypoechogenicity intrasplenic masses of. A standard whole-body CT showed a moderate splenomegaly with splenic nodular masses with high density that suggested splenomas. Technetium-99m heat-damaged red blood cells showed multiple focal rounded masses with radiotracer activity indicating functioning intrasplenic tissue and regenerating nodules, whereas the rest of the parenchyma was nonfunctioning.
