Abstract
Background Inflammation plays a key role in psoriasis. Statins reduce inflammatory markers. However, data in the literature are limited regarding the effect of statins in psoriasis patients. Objective To examine the role of statin therapy in psoriasis. Methods We performed a retrospective chart review of 232 psoriasis patients. Psoriasis severity was measured by the percentage of body surface area covered by psoriatic lesions. It was recorded at two time points: (1) the last visit during which a new psoriasis medication was started and (2) the patient's most recent clinic visit. Subjects were divided according to statin use status. Results Although the statin users had a greater reduction in psoriasis severity, the difference did not reach statistical significance. Conclusions Our data suggest that future work regarding the impact of statin use on psoriasis severity is warranted.