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Substance P expands proinflammatory, IL-31-secreting M2 macrophages in human skin ex vivo through neurokinin-1 receptor-mediated signaling and increased dermal periostin expression
Journal article   Peer reviewed

Substance P expands proinflammatory, IL-31-secreting M2 macrophages in human skin ex vivo through neurokinin-1 receptor-mediated signaling and increased dermal periostin expression

Sofia M Perez, Jennifer Gherardini, Mounika Vattigunta, Tatiana Gomez Gomez, Wendy Lee, Leigh Nattkemper, Gil Yosipovitch, Jérémy Chéret and Ralf Paus
Journal of investigative dermatology, Vol.146(4)
2025-10-14
PMID: 41101631

Abstract

atopic dermatitis inflammation Neuromediators human skin Macrophage

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