Synthesis, Nicotinic Acetylcholine Receptor Binding, and in Vitro and in Vivo Pharmacological Properties of 2′-Fluoro-(substituted thiophenyl)deschloroepibatidine Analogues

Pauline W Ondachi; Ana H Castro; Benjamin Sherman; Charles W Luetje; M. Imad Damaj; S. Wayne Mascarella; Hernán A Navarro; F. I Carroll

doi:10.1021/acschemneuro.6b00252

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Synthesis, Nicotinic Acetylcholine Receptor Binding, and in Vitro and in Vivo Pharmacological Properties of 2′-Fluoro-(substituted thiophenyl)deschloroepibatidine Analogues

Journal article

Peer reviewed

Synthesis, Nicotinic Acetylcholine Receptor Binding, and in Vitro and in Vivo Pharmacological Properties of 2′-Fluoro-(substituted thiophenyl)deschloroepibatidine Analogues

Pauline W Ondachi, Ana H Castro, Benjamin Sherman, Charles W Luetje, M. Imad Damaj, S. Wayne Mascarella, Hernán A Navarro and F. I Carroll

ACS chemical neuroscience, Vol.8(1), pp.115-127

2017-01-18

DOI: https://doi.org/10.1021/acschemneuro.6b00252

PMID: 27726337

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Collaboration types: Domestic collaboration
Citation topics: 1 Clinical & Life Sciences; 1.5 Neuroscience; 1.5.894 Nicotine
Web Of Science research areas: Biochemistry & Molecular Biology; Chemistry, Medicinal; Neurosciences
ESI research areas: Neuroscience & Behavior

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Title: Synthesis, Nicotinic Acetylcholine Receptor Binding, and in Vitro and in Vivo Pharmacological Properties of 2′-Fluoro-(substituted thiophenyl)deschloroepibatidine Analogues
Creators: Pauline W Ondachi - Research Triangle Institute, P.O. Box 12194, Research Triangle Park, North Carolina 27709, United States
Ana H Castro - Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, Florida 33101, United States
Benjamin Sherman - Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, Florida 33101, United States
Charles W Luetje - Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, Florida 33101, United States
M. Imad Damaj - Department of Pharmacology, Virginia Commonwealth University Medical Campus, P.O. Box 980615, Richmond, Virginia 23298-0613, United States
S. Wayne Mascarella - Research Triangle Institute, P.O. Box 12194, Research Triangle Park, North Carolina 27709, United States
Hernán A Navarro - Research Triangle Institute, P.O. Box 12194, Research Triangle Park, North Carolina 27709, United States
F. I Carroll - Research Triangle Institute, P.O. Box 12194, Research Triangle Park, North Carolina 27709, United States
Publication Details: ACS chemical neuroscience, Vol.8(1), pp.115-127
Academic Unit: Miller School of Medicine; Molecular and Cellular Pharmacology Research
Language: English
Resource Type: Journal article
PMID: 27726337
Record Identifier: 991031578354102976