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The Birds, the Bees, and Innate Immunity
Journal article   Open access  Peer reviewed

The Birds, the Bees, and Innate Immunity

Glen N Barber
Immunity (Cambridge, Mass.), Vol.46(4), pp.521-522
2017-04-18
PMID: 28423330

Abstract

Spermatozoa Animals Fertilization - physiology DNA Female Male Fertilization - immunology Immunity, Innate Cytoplasm Oocytes
The cytoplasm is usually a DNA-free zone, but during fertilization, sperm DNA enters oocyte cytoplasm and could potentially trigger a response. Abe et al. (2017) identify NLRP14 as a germ-cell-specific negative regulator of DNA sensing that may be of particular importance during fertilization.
url
https://doi.org/10.1016/j.immuni.2017.04.002View
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Citation topics
1 Clinical & Life Sciences
1.6 Immunology
1.6.609 Toll-like Receptors
Web Of Science research areas
Immunology
ESI research areas
Immunology

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#3 Good Health and Well-Being

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