The DISCUSS Project: Revised Points to Consider for the Derivation of Induced Pluripotent Stem Cell Lines From Previously Collected Research Specimens

Geoffrey P Lomax; Sara Chandros Hull; Rosario Isasi

doi:10.5966/sctm.2014-0192

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The DISCUSS Project: Revised Points to Consider for the Derivation of Induced Pluripotent Stem Cell Lines From Previously Collected Research Specimens

Journal article

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The DISCUSS Project: Revised Points to Consider for the Derivation of Induced Pluripotent Stem Cell Lines From Previously Collected Research Specimens

Geoffrey P Lomax, Sara Chandros Hull and Rosario Isasi

Stem cells translational medicine, Vol.4(2), pp.123-129

2015-02

DOI: https://doi.org/10.5966/sctm.2014-0192

PMCID: PMC4303360

PMID: 25561681

Abstract

Cell Line

Drug Discovery

Humans

Induced Pluripotent Stem Cells

Specimen Handling

Stem Cell Research

Human somatic cell reprogramming is a leading technology for accelerating disease modeling and drug discovery. The Deriving Induced Stem Cells Using Stored Specimens (DISCUSS) project is a consensus-building initiative designed to consider how human somatic cells obtained under general biomedical research protocols can be used in induced pluripotent stem cell (iPSC) derivation. We previously published a draft list of points to consider for the use of previously collected specimens in iPSC research and then initiated a structured feedback and comment process. Here, we present a summary of this feedback and revised list of points to consider.

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.102 Stem Cell Research; 1.102.622 Pluripotency
Web Of Science research areas: Cell & Tissue Engineering
ESI research areas: Molecular Biology & Genetics

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Title: The DISCUSS Project: Revised Points to Consider for the Derivation of Induced Pluripotent Stem Cell Lines From Previously Collected Research Specimens
Creators: Geoffrey P Lomax - California Institute for Regenerative Medicine, San Francisco, California, USA; glomax@cirm.ca.gov glomax@lmi.net
Sara Chandros Hull - Office of the Clinical Director, National Human Genome Research Institute and Department of Bioethics, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
Rosario Isasi - Centre of Genomics and Policy, Faculty of Medicine, Department of Human Genetics, McGill University, Montreal, Quebec, Canada
Publication Details: Stem cells translational medicine, Vol.4(2), pp.123-129
Academic Unit: Miller School of Medicine; John P. Hussman Institute for Human Genomics; UMMG Dept of Human Genetics (Dr. John T. Macdonald Foundation)
Language: English
Resource Type: Journal article
PMID: 25561681
PMCID: PMC4303360
Record Identifier: 991031614044502976