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The IlluminOss photodynamic bone stabilization system: novel technology with broad application in orthopaedic fracture fixation
Journal article   Peer reviewed

The IlluminOss photodynamic bone stabilization system: novel technology with broad application in orthopaedic fracture fixation

Roy Y. Miloh, Hannah A. Mosher, D. Wood Kimbrough, H. Thomas Temple, Francis J. Hornicek, Brooke Crawford and Erik J. Geiger
Expert review of medical devices, pp.1-13
2026-02-08
PMID: 41638693

Abstract

Fixation fracture illuminoss internal fixation minimally invasive pathologic fracture photodynamic stabilization traumatic fracture

IntroductionThe number of individuals aged 50 years or older at risk of an osteoporotic fracture was 158 million worldwide in 2010, a number projected to double by 2040. Optimization of fracture fixation techniques for osteoporotic and pathologic fractures and developing novel implants addressing growing demand are paramount.Areas coveredThis manuscript details clinical applications of the IlluminOss Photodynamic Bone Stabilization System (PBSS), surgical techniques, the novelty of the device, and highlights early clinical results.Expert opinionThe IlluminOss PBSS represents a new implant category in fracture fixation with broad applications. The system's intraoperative flexibility permits insertion with minimal soft tissue damage, enhancing wound healing and recovery - particularly advantageous for oncology patients requiring adjuvant chemotherapy. The implant provides non-traditional access points, expanding indications for intramedullary fixation. The PBSS can provide stand-alone fixation or augment traditional plate-and-screw constructs. The balloon's conformity to curved trajectories provides creative alternatives to pelvic fixation and can support complex acetabular arthroplasty. The PBSS can help prevent allograft fractures and has applications in limb lengthening/deformity correction. Early clinical data show high procedural success, significant pain reduction, and improved function comparable to standard fixation. Future work will assess its use in contaminated fractures or osteomyelitis, due to blue light's potential antimicrobial effects.

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