Two predominant molecular subtypes of spinal meningioma: thoracic NF2-mutant tumors strongly associated with female sex, and cervical AKT1-mutant tumors originating ventral to the spinal cord

Lingyang Hua; Majd Alkhatib; Dino Podlesek; Leila Günther; Thomas Pinzer; Matthias Meinhardt; Silke Zeugner; Sylvia Herold; Daniel P Cahill; Priscilla K Brastianos; Erik A Williams; Victoria E Clark; Ganesh M Shankar; Hiroaki Wakimoto; Leihao Ren; Jiawei Chen; Ye Gong; Gabriele Schackert; Tareq A Juratli

doi:10.1007/s00401-022-02474-9

Back

Two predominant molecular subtypes of spinal meningioma: thoracic NF2-mutant tumors strongly associated with female sex, and cervical AKT1-mutant tumors originating ventral to the spinal cord

Journal article

Peer reviewed

Two predominant molecular subtypes of spinal meningioma: thoracic NF2-mutant tumors strongly associated with female sex, and cervical AKT1-mutant tumors originating ventral to the spinal cord

Lingyang Hua, Majd Alkhatib, Dino Podlesek, Leila Günther, Thomas Pinzer, Matthias Meinhardt, Silke Zeugner, Sylvia Herold, Daniel P Cahill, Priscilla K Brastianos, …

Acta neuropathologica, Vol.144(5), pp.1053-1055

2022-11-01

DOI: https://doi.org/10.1007/s00401-022-02474-9

PMID: 35943573

Appears in Miller School of Medicine - Latest Publications

Abstract

Female

Humans

Meningeal Neoplasms - genetics

Meningeal Neoplasms - pathology

Meningioma - genetics

Meningioma - pathology

Proto-Oncogene Proteins c-akt

Spinal Cord Neoplasms - genetics

Spinal Cord Neoplasms - pathology

Files and links (1)

url

https://doi.org/10.1007/s00401-022-02474-9View

Published (Version of record) Open

Metrics

1 Record Views

See more details

Details

Title: Two predominant molecular subtypes of spinal meningioma: thoracic NF2-mutant tumors strongly associated with female sex, and cervical AKT1-mutant tumors originating ventral to the spinal cord
Creators: Lingyang Hua - Huashan Hospital
Majd Alkhatib - University Hospital Carl Gustav Carus
Dino Podlesek - University Hospital Carl Gustav Carus
Leila Günther - University Hospital Carl Gustav Carus
Thomas Pinzer - University Hospital Carl Gustav Carus
Matthias Meinhardt - University Hospital Carl Gustav Carus
Silke Zeugner - University Hospital Carl Gustav Carus
Sylvia Herold - University Hospital Carl Gustav Carus
Daniel P Cahill - Massachusetts General Hospital
Priscilla K Brastianos - Massachusetts General Hospital
Erik A Williams - Massachusetts General Hospital
Victoria E Clark - Harvard Medical School
Ganesh M Shankar - Harvard University
Hiroaki Wakimoto - Massachusetts General Hospital
Leihao Ren - Huashan Hospital
Jiawei Chen - Huashan Hospital
Ye Gong - Huashan Hospital
Gabriele Schackert - Technische Universität Dresden
Tareq A Juratli - Massachusetts General Hospital
Publication Details: Acta neuropathologica, Vol.144(5), pp.1053-1055
Academic Unit: Miller School of Medicine; UMMG Department of Pathology
Language: English
Resource Type: Journal article
PMID: 35943573
Record Identifier: 991032796000902976