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Ultraviolet induced fluorescent dermoscopy for the diagnosis of skin tumors: A multicenter study
Journal article   Peer reviewed

Ultraviolet induced fluorescent dermoscopy for the diagnosis of skin tumors: A multicenter study

Cristian Navarrete-Dechent, Pawel Pietkiewicz, Alvaro Abarzua-Araya, Rosario Agüero, Stephen W Dusza, Julien Anriot, Javiera Garcés, Sofía Villagrán, Sergio Bustos, Sebastián González-Valdés, …
Journal of the American Academy of Dermatology, Vol.94(3)
2025-10-30
PMID: 41176254

Abstract

dermatoscopy skin cancer fluorescence ultraviolet basal cell carcinoma melanoma seborrheic keratosis dermoscopy
Ultraviolet-induced fluorescent dermoscopy (UVFD) is a novel dermoscopic technique that has shown potential to improve diagnostic accuracy for select conditions in small case series. However, its performance has not yet been assessed in a large cohort of cutaneous tumors. To evaluate the role of UVFD in cutaneous tumors. This retrospective, multicenter study included consecutive lesions assessed at three tertiary care clinics in Chile, France, and Poland. Standard polarized dermoscopic images and UVFD images were independently reviewed by two expert dermoscopists, with consensus evaluation. Established dermoscopic criteria, as well as border definition and the presence of "ochre color," were specifically assessed. 551 lesions were included. The most frequent diagnosis was basal cell carcinoma (28.2%) followed by melanocytic nevus (18.6%), and melanoma (12.8%). Keratin, comedo-like openings, and fissures and ridges were better seen under UVFD. The border definition of lesions was also better seen under UVFD. Ochre color was seen under UVFD mostly in invasive melanomas. Retrospective study. Some tumors were underrepresented. UVFD enhances specific keratin-related dermoscopic structures and colors. It also provides for better border delineation and may help in identifying invasive melanomas via the presence of ochre color.

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