Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ε4, and the Risk of Late-Onset Alzheimer Disease in African Americans

Christiane REITZ; Gyungah JUN; Denis EVANS; Philip L DE JAGER; Paul K CRANE; Joseph D BUXBAUM; Jill R MURRELL; Towfique RAJ; Nilufer ERTEKIN-TANER; Mark LOGUE; Clinton T BALDWIN; Robert C GREEN; Adam NAJ; Lisa L BARNES; Laura B CANTWELL; M DANIELE FALLIN; Rodney C. P GO; Patrick GRIFFITH; Thomas O OBISESAN; Jennifer J MANLY; Kathryn L LUNETTA; M ILYAS KAMBOH; Oscar L LOPEZ; Ruchita RAJBHANDARY; David A BENNETT; Hugh HENDRIE; Kathleen S HALL; Alison M GOATE; Goldie S BYRD; Walter A KUKULL; Tatiana M FOROUD; Jonathan L HAINES; Lindsay A FARRER; Margaret A PERICAK-VANCE; BADRI NARAYAN BADRI NARAYAN VARDARAJAN; Gerard D SCHELLENBERG; Richard MAYEUX; Li-San WANG; Otto VALLADARES; Chiao-Feng LIN; Eric B LARSON; Neill R GRAFF-RADFORD

doi:10.1001/jama.2013.2973

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Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ε4, and the Risk of Late-Onset Alzheimer Disease in African Americans

Journal article

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Peer reviewed

Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ε4, and the Risk of Late-Onset Alzheimer Disease in African Americans

Christiane REITZ, Gyungah JUN, Denis EVANS, Philip L DE JAGER, Paul K CRANE, Joseph D BUXBAUM, Jill R MURRELL, Towfique RAJ, Nilufer ERTEKIN-TANER, Mark LOGUE, …

JAMA : the journal of the American Medical Association, Vol.309(14), pp.1483-1492

2013

DOI: https://doi.org/10.1001/jama.2013.2973

PMCID: PMC3667653

PMID: 23571587

Abstract

Neurology

Organic mental disorders. Neuropsychology

General aspects

Psychology. Psychoanalysis. Psychiatry

Adult and adolescent clinical studies

Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases

Psychopathology. Psychiatry

Biological and medical sciences

Medical sciences

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307 Times Cited - Web of Science

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Highly Cited Paper

Collaboration types: Domestic collaboration
Citation topics: 1 Clinical & Life Sciences; 1.52 Neurodegenerative Diseases; 1.52.57 Alzheimer's Disease
Web Of Science research areas: Clinical Neurology
ESI research areas: Clinical Medicine

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Title: Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ε4, and the Risk of Late-Onset Alzheimer Disease in African Americans
Creators: Christiane REITZ - Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States
Gyungah JUN - Department of Medicine (Genetics Program), Boston University, Boston, Massachusetts, United States
Denis EVANS - Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States
Philip L DE JAGER - Program in Translational Neuropsychiatric Genomics, Department of Neurology, Brigham & Women's Hospital, Boston, Massachusetts, United States
Paul K CRANE - Department of Medicine and National Alzheimer's Coordinating Center, University of Washington, Seattle, United States
Joseph D BUXBAUM - Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States
Jill R MURRELL - Department of Medical and Molecular Genetics, Indiana University, United States
Towfique RAJ - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Nilufer ERTEKIN-TANER - Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States
Mark LOGUE - Department of Medicine (Genetics Program), Boston University, Boston, Massachusetts, United States
Clinton T BALDWIN - Department of Medicine (Genetics Program), Boston University, Boston, Massachusetts, United States
Robert C GREEN - Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States
Adam NAJ - Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States
Lisa L BARNES - Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, United States
Laura B CANTWELL - Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States
M DANIELE FALLIN - Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States
Rodney C. P GO - Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States
Patrick GRIFFITH - Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States
Thomas O OBISESAN - Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States
Jennifer J MANLY - Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States
Kathryn L LUNETTA - Department of Biostatistics, Boston University, Boston, Massachusetts, United States
M ILYAS KAMBOH - Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States
Oscar L LOPEZ - Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States
Ruchita RAJBHANDARY - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
David A BENNETT - Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, United States
Hugh HENDRIE - Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States
Kathleen S HALL - Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States
Alison M GOATE - Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States
Goldie S BYRD - Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States
Walter A KUKULL - Department of Epidemiology, University of Washington, Seattle, United States
Tatiana M FOROUD - Department of Medical and Molecular Genetics, Indiana University, United States
Jonathan L HAINES - Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States
Lindsay A FARRER - Department of Neurology, Boston University, Boston, Massachusetts, United States
Margaret A PERICAK-VANCE - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
BADRI NARAYAN BADRI NARAYAN VARDARAJAN - Department of Medicine (Genetics Program), Boston University, Boston, Massachusetts, United States
Gerard D SCHELLENBERG - Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States
Richard MAYEUX - Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States
Li-San WANG - Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States
Otto VALLADARES - Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States
Chiao-Feng LIN - Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States
Eric B LARSON - Department of Medicine and National Alzheimer's Coordinating Center, University of Washington, Seattle, United States
Neill R GRAFF-RADFORD - Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States
Publication Details: JAMA : the journal of the American Medical Association, Vol.309(14), pp.1483-1492
Publisher: American Medical Association; Chicago, IL
Academic Unit: Miller School of Medicine; John P. Hussman Institute for Human Genomics; UMMG Dept of Human Genetics (Dr. John T. Macdonald Foundation)
Language: English
Resource Type: Journal article
PMID: 23571587
PMCID: PMC3667653
Record Identifier: 991031561020502976