Where to Next for Optimizing Adherence in Large-Scale Trials of Continuous Positive Airway Pressure?

Amy M Sawyer; Douglas M Wallace; Luis F Buenaver; Alexa J Watach; Amy Blase; Bruno Saconi; Sanjay R Patel; Samuel T Kuna; Naresh M Punjabi

doi:10.1016/j.jsmc.2020.10.007

Journal article

Where to Next for Optimizing Adherence in Large-Scale Trials of Continuous Positive Airway Pressure?

Amy M Sawyer, Douglas M Wallace, Luis F Buenaver, Alexa J Watach, Amy Blase, Bruno Saconi, Sanjay R Patel, Samuel T Kuna and Naresh M Punjabi

Sleep medicine clinics, Vol.16(1), pp.125-144

2021-03

DOI: https://doi.org/10.1016/j.jsmc.2020.10.007

PMID: 33485525

Abstract

Telemedicine

Continuous positive airway pressure

Health behavior

Health education

Obstructive sleep apnea

Patient compliance

Behavioral economics

Controlled clinical trial

Large-scale randomized trials of positive airway pressure (PAP) efficacy have been largely negative but PAP adherence was notably suboptimal across the trials. To address this limitation, evidence-based PAP adherence protocols embedded within the larger trial protocol are recommended. The complexity of such protocols depends on adequacy of resources, including funding and inclusion of behavioral scientist experts on the scientific team, and trial-specific considerations (eg, target population) and methods. Recommendations for optimizing PAP adherence in large-scale trials are set forth that address rigor and reproducibility.

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Details

Title: Where to Next for Optimizing Adherence in Large-Scale Trials of Continuous Positive Airway Pressure?
Creators: Amy M Sawyer - Department of Biobehavioral Health Science, University of Pennsylvania School of Nursing, 418 Curie Boulevard, Claire Fagin Hall, Room 349, Philadelphia, PA 19104, USA
Douglas M Wallace - Department of Neurology, Sleep Medicine Division, University of Miami Miller School of Medicine, 1201 Northwest 16th Street, Room A212, Miami, FL 33125, USA
Luis F Buenaver - Johns Hopkins Behavioral Sleep Medicine Program, Johns Hopkins University School of Medicine, 5510 Nathan Shock Drive, Suite 100, Baltimore, MD 21224-6823, USA
Alexa J Watach - University of Pennsylvania Perelman School of Medicine, Center for Sleep and Circadian Neurobiology, Philadelphia, PA, USA
Amy Blase - ResMed Corporation, 9001 Spectrum Center Boulevard, San Diego, CA 92123, USA
Bruno Saconi - University of Pennsylvania School of Nursing, 418 Curie Boulevard, Claire Fagin Hall, Philadelphia, PA 19104, USA
Sanjay R Patel - Center for Sleep and Cardiovascular Outcomes Research, University of Pittsburgh, 3609 Forbes Avenue, 2nd Floor, Room 108, Pittsburgh, PA 15213, USA
Samuel T Kuna - University of Pennsylvania Perelman School of Medicine, Center for Sleep and Circadian Neurobiology, Philadelphia, PA, USA
Naresh M Punjabi - Division of Pulmonary, Critical Care, and Sleep Medicine, University of Miami, Miller School of Medicine, 1951 NW 7th Avenue, Miami, FL 33136, USA
Publication Details: Sleep medicine clinics, Vol.16(1), pp.125-144
Publisher: Elsevier Inc
Academic Unit: Miller School of Medicine; UMMG Department of Neurology; UMMG Dept of Medicine - Pulmonary, Critical Care & Sleep Medicine
Language: English
Resource Type: Journal article
PMID: 33485525
Record Identifier: 991031599263902976