White Blood Cell Counts, Lymphocyte Subsets, and Incident Diabetes Mellitus in Women Living With and Without HIV

Carrie D Johnston; Donald R Hoover; Qiuhu Shi; Anjali Sharma; David B Hanna; Kathryn Anastos; Phyllis C Tien; Margaret Fischl; Deborah Gustafson; Amanda Spence; Roksana Karim; Audrey French; Michael Schneider; Adaora A Adimora; Caitlin Moran; Deborah Konkle-Parker; Marshall J Glesby

doi:10.1089/AID.2019.0174

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White Blood Cell Counts, Lymphocyte Subsets, and Incident Diabetes Mellitus in Women Living With and Without HIV

Journal article

Peer reviewed

White Blood Cell Counts, Lymphocyte Subsets, and Incident Diabetes Mellitus in Women Living With and Without HIV

Carrie D Johnston, Donald R Hoover, Qiuhu Shi, Anjali Sharma, David B Hanna, Kathryn Anastos, Phyllis C Tien, Margaret Fischl, Deborah Gustafson, Amanda Spence, …

AIDS research and human retroviruses, Vol.36(2), pp.131-133

2020-02

DOI: https://doi.org/10.1089/AID.2019.0174

PMID: 31709815

Abstract

United States - epidemiology

Prospective Studies

HIV Infections - epidemiology

Humans

Middle Aged

CD4 Lymphocyte Count

Lymphocyte Subsets - immunology

HIV Infections - immunology

CD4-CD8 Ratio

Diabetes Complications - immunology

Diabetes Mellitus - immunology

Diabetes Complications - virology

Diabetes Mellitus - epidemiology

HIV Infections - complications

Diabetes Complications - epidemiology

Adult

Female

Leukocyte Count

CD8-Positive T-Lymphocytes - immunology

Diabetes mellitus (DM) is associated with expansion of proinflammatory lymphocyte subsets. We investigated the relationship of total white blood cell (WBC) count and lymphocyte subsets with incident DM in the Women's Interagency HIV Study (WIHS). Higher CD4 and CD8 T cell counts, lymphocyte count, and total WBC count were associated with incident DM among both women with and without HIV, although the association of CD8 was not statistically significant among women without HIV.

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Collaboration types: Domestic collaboration
Citation topics: 1 Clinical & Life Sciences; 1.66 HIV; 1.66.1372 Lipodystrophy
Web Of Science research areas: Immunology; Infectious Diseases; Virology
ESI research areas: Immunology

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Source: InCites

Details

Title: White Blood Cell Counts, Lymphocyte Subsets, and Incident Diabetes Mellitus in Women Living With and Without HIV
Creators: Carrie D Johnston - Department of Medicine, Weill Cornell Medical College, New York, New York
Donald R Hoover - Department of Statistics and Biostatistics and Institute for Health, Health Care Policy and Aging Research, Rutgers the State University of New Jersey, New Brunswick, New Jersey
Qiuhu Shi - Department of Epidemiology and Community Health, School of Health Sciences and Practice, New York Medical College, Valhalla, New York
Anjali Sharma - Department of Medicine, Albert Einstein College of Medicine, Bronx, New York
David B Hanna - Department of Epidemiology, Albert Einstein College of Medicine, Bronx, New York
Kathryn Anastos - Department of Medicine, Albert Einstein College of Medicine, Bronx, New York
Phyllis C Tien - Department of Medicine, University of California-San Francisco and the Department of Veterans Affairs, San Francisco, California
Margaret Fischl - Department of Medicine, University of Miami School of Medicine, Miami, Florida
Deborah Gustafson - Department of Neurology, SUNY Downstate Medical Center, Brooklyn, New York
Amanda Spence - Department of Medicine, MedStar Georgetown University Health System, Washington, District of Columbia
Roksana Karim - Department of Preventive Medicine, USC Keck School of Medicine, Los Angeles, California
Audrey French - Department of Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, Illinois
Michael Schneider - Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
Adaora A Adimora - Departments of Medicine and Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Caitlin Moran - Department of Medicine, Emory Healthcare, Atlanta, Georgia
Deborah Konkle-Parker - Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi
Marshall J Glesby - Department of Medicine, Weill Cornell Medical College, New York, New York
Publication Details: AIDS research and human retroviruses, Vol.36(2), pp.131-133
Publisher: United States
Grant note: U01 HD032632 / NICHD NIH HHS U01 HL146194 / NHLBI NIH HHS U01 AI103397 / NIAID NIH HHS K01 HL137557 / NHLBI NIH HHS U01 AI042590 / NIAID NIH HHS U01 AI031834 / NIAID NIH HHS U01 AI035004 / NIAID NIH HHS U01 AI034993 / NIAID NIH HHS U01 AI103408 / NIAID NIH HHS U01 AI103401 / NIAID NIH HHS U01 AI103390 / NIAID NIH HHS P30 AI050410 / NIAID NIH HHS T32 AI007613 / NIAID NIH HHS U01 AI034994 / NIAID NIH HHS U01 AI034989 / NIAID NIH HHS
Academic Unit: Miller School of Medicine; UMMG Dept of Medicine - Infectious Diseases
Language: English
Resource Type: Journal article
PMID: 31709815
Record Identifier: 991031577336302976