Abstract
Arrhythmogenic cardiomyopathy (ACM) is a genetically inherited heart disease, clinically characterized by ventricular arrhythmias and impairment of ventricular systolic function, and pathologically by fibro-fatty changes in the myocardium.1 In this study, we have explored the differential gene expression and conducted downstream functional genomic analysis using 3 datasets retrieved from the Gene Expression Omnibus (GEO) database. We aimed to highlight the key genomic changes occurring in this subtype of cardiomyopathy.
