Expertise
Role of noncoding RNAs in schizophrenia.
Role of microRNAs in the mechanisms of drug dependence.
Regulatory RNAs as mediators and biomarkers in Alzheimer's Disease.
Discovery and development of nociceptin receptor ligands in alcohol dependence.
Noncoding RNAs as epigenomic modulators in Alzheimer's Disease.
Discovery of potent and selective neuropeptide Y Y2 receptor antagonist probes.
Comprehensive analysis of the FMR1 locus transcriptional landscape.
Wahlestedt has a long-standing interest in non-protein-coding RNA (epigenetics) and pioneered various uses of antisense RNA, siRNA and small molecules that target RNA.
We study the role of the noncoding RNAs in schizophrenia, the role of microRNA in the mechanisms of drug dependency, regulatory RNA’s as mediators and biomarkers in Alzheimer’s Disease, the discovery and development of nociception receptor ligands in alcohol dependence, noncoding RNAsepigenomic modulators in Alzheimer’s Disease, the discovery of a potent and selective neuropeptide YY2 receptor antagonist probes, and comprehensive analysis of FRM1 locus transcriptional landscape.