Dr. Brosco’s research includes an analysis of the history of health care for children in early 20th century Philadelphia, the historical epidemiology of intellectual disability, and the history of newborn screening in the US. With Diane Paul, he is co-author of The PKU Paradox: A Short History of a Genetic Disease (Johns Hopkins Press, 2013). His current work integrates history, ethics, and clinical practice to forge systems-level approaches to improving child health, especially regarding large-scale screening programs.