Ion channels and transporters in glia-neurons functional interaction
DEG/ENaC channels in sensory perception.
DEG/ENaC channels functional properties and neurotoxicity
Employing the powerful model organism, C. elegans, my laboratory is interested in the role of DEG/ENaC ion channels in sensory perception and neurodegeneration. These voltage- independent Na+ channels function as trimers in an extraordinary range of biological processes including several senses, transepithelial transport, and have been linked to human diseases.